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RNA structures and folding: from conventional to new issues in structure predictions.

by: P Schuster, PF Stadler, A Renner
Curr Opin Struct Biol, Vol. 7, No. 2. (April 1997), pp. 229-235.


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Prediction and modeling of RNA structures has become an indispensable tool of biological research disciplines. Currently, reliable predictions require massive input of experimental data. Structure-forming elements are conventional base pairs, as well as a rapidly increasing repertoire of novel structural motifs. New developments extend structural analysis beyond the one-sequence/one-structure paradigm and allow questions that are relevant to molecular evolution to be answered.


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