Revised methods for the Salmonella mutagenicity test.

by: DM Maron, BN Ames

Mutat Res, Vol. 113, No. 3-4. (May 1983), pp. 173-215.

View FullText article

Pubmed, Hubmed

Reviews [Write a review of this article]

There are no reviews of this article

Find related articles from these CiteULike users

cherrie, CAOS (group)

Find related articles with these CiteULike tags

1983, ames, carcinogen, carcinogenicity, medsci302, mutagen, mutagenicity, revertant, revised, salmonella, test

Abstract

The methods for detecting carcinogens and mutagens with the Salmonella mutagenicity test were described previously (Ames et al., 1975b). The present paper is a revision of the methods. Two new tester strains, a frameshift strain (TA97) and a strain carrying an ochre mutation on a multicopy plasmid (TA102), are added to the standard tester set. TA97 replaces TA1537. TA1535 and TA1538 are removed from the recommended set but can be retained at the option of the investigator. TA98 and TA100 are retained. We discuss other special purpose strains and present some minor changes in procedure, principally in the growth, storage, and preservation of the tester strains. Two substitutions are made in diagnostic mutagens to eliminate MNNG and 9-aminoacridine. Some test modifications are discussed.

@article{citeulike:779904, abstract = {The methods for detecting carcinogens and mutagens with the Salmonella mutagenicity test were described previously (Ames et al., 1975b). The present paper is a revision of the methods. Two new tester strains, a frameshift strain (TA97) and a strain carrying an ochre mutation on a multicopy plasmid (TA102), are added to the standard tester set. TA97 replaces TA1537. TA1535 and TA1538 are removed from the recommended set but can be retained at the option of the investigator. TA98 and TA100 are retained. We discuss other special purpose strains and present some minor changes in procedure, principally in the growth, storage, and preservation of the tester strains. Two substitutions are made in diagnostic mutagens to eliminate MNNG and 9-aminoacridine. Some test modifications are discussed.}, author = {Maron, D. M. and Ames, B. N. }, citeulike-article-id = {779904}, issn = {0027-5107}, journal = {Mutat Res}, keywords = {1983, ames, carcinogen, carcinogenicity, medsci302, mutagen, mutagenicity, revertant, revised, salmonella, test}, month = {May}, number = {3-4}, pages = {173--215}, posted-at = {2006-07-30 05:03:20}, priority = {3}, title = {Revised methods for the Salmonella mutagenicity test.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/6341825}, volume = {113}, year = {1983} }

RIS record

TY - JOUR ID - citeulike:779904 L3 - citeulike-article-id:779904 TI - Revised methods for the Salmonella mutagenicity test. JF - Mutat Res VL - 113 IS - 3-4 SP - 173 EP - 215 SN - 0027-5107 N2 - The methods for detecting carcinogens and mutagens with the Salmonella mutagenicity test were described previously (Ames et al., 1975b). The present paper is a revision of the methods. Two new tester strains, a frameshift strain (TA97) and a strain carrying an ochre mutation on a multicopy plasmid (TA102), are added to the standard tester set. TA97 replaces TA1537. TA1535 and TA1538 are removed from the recommended set but can be retained at the option of the investigator. TA98 and TA100 are retained. We discuss other special purpose strains and present some minor changes in procedure, principally in the growth, storage, and preservation of the tester strains. Two substitutions are made in diagnostic mutagens to eliminate MNNG and 9-aminoacridine. Some test modifications are discussed. KW - 1983 KW - ames KW - carcinogen KW - carcinogenicity KW - medsci302 KW - mutagen KW - mutagenicity KW - revertant KW - revised KW - salmonella KW - test AU - Maron, DM AU - Ames, BN PY - 1983/05// UR - http://view.ncbi.nlm.nih.gov/pubmed/6341825 ER -

RIS BibTeX