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Laboratory Investigation

Статьи последних нескольких выпусков журнала Laboratory Investigation © Nature Publishing Group
  • The mitochondrial permeability transition, and oxidative and nitrosative stress in the mechanism of copper toxicity in cultured neurons and astrocytes
    Laboratory Investigation, Vol. aop, No. current.
    by Pichili VB Reddy, Kakulavarapu, Michael D Norenberg
  • The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma
    Laboratory Investigation, Vol. aop, No. current.
    by Motoko Sasaki, Hiroko Ikeda, Keita Itatsu, Junpei Yamaguchi, Seiko Sawada, Hiroshi Minato, Tetsuo Ohta, Yasuni Nakanuma
  • Expression of specific hepatocyte and cholangiocyte transcription factors in human liver disease and embryonic development
    Laboratory Investigation, Vol. aop, No. current.
    by Pallavi B Limaye, Gabriela Alarcón, Andrew L Walls, Michael A Nalesnik, George K Michalopoulos, Anthony J Demetris, Erin R Ochoa
  • Aggressive melanoma cells escape from BMP7-mediated autocrine growth inhibition through coordinated Noggin upregulation
    Laboratory Investigation, Vol. aop, No. current.
    by Mei-Yu Hsu, Sherry A Rovinsky, Chiou-Yan Lai, Shadi Qasem, Xiaoming Liu, Joan How, John F Engelhardt, George F Murphy
  • Clinical and biological implications of CD133-positive and CD133-negative cells in glioblastomas
    Laboratory Investigation, Vol. aop, No. current.
    by Kyeung M Joo, Shi Y Kim, Xun Jin, Sang Y Song, Doo-Sik Kong, Jung-Ii Lee, Ji W Jeon, Mi H Kim, Bong G Kang, Yong Jung, Juyoun Jin, Seung-Chyul Hong, Woong-Yang Park, Dong-Sup Lee, Hyunggee Kim, Do-Hyun Nam
  • Expression of galectin-3 in the tumor immune response in colon cancer
    Laboratory Investigation, Vol. aop, No. current.
    by Patrick Dumont, Alix Berton, Nathalie Nagy, Flavienne Sandras, Sandrine Tinton, Pieter Demetter, Françoise Mascart, Abdelmounaaïm Allaoui, Christine Decaestecker, Isabelle Salmon
  • Human hepatocellular carcinoma expresses specific PCNA isoforms: an in vivo and in vitro evaluation
    Laboratory Investigation, Vol. aop, No. current.
    by Annamaria Venturi, Fabrizio D Piaz, Catia Giovannini, Laura Gramantieri, Pasquale Chieco, Luigi Bolondi
  • Stat4 suppresses the proliferation of connective tissue-type mast cells
    Laboratory Investigation, Vol. aop, No. current.
    by Tatsuki R Kataoka, Yasuko Nishizawa
  • Autoantibodies and neurodegeneration in multiple sclerosis
    Laboratory Investigation, Vol. aop, No. current.
    by Tamara Vyshkina, Bernadette Kalman
  • Laser microdissection and primary cell cultures improve pharmacogenetic analysis in pancreatic adenocarcinoma
    Laboratory Investigation, Vol. aop, No. current.
    by Niccola Funel, Elisa Giovannetti, Marco Del Chiaro, Valentina Mey, Luca E Pollina, Sara Nannizzi, Ugo Boggi, Simona Ricciardi, Mario Del Tacca, Generoso Bevilacqua, Franco Mosca, Romano Danesi, Daniela Campani
  • Cellular origins of adult human islet in vitro dedifferentiation
    Laboratory Investigation, Vol. aop, No. current.
    by Stephen C Hanley, Amélie Pilotte, Bernard Massie, Lawrence Rosenberg
  • Deterioration of atherosclerosis in mice lacking angiotensin II type 1A receptor in bone marrow-derived cells
    Laboratory Investigation, Vol. aop, No. current.
    by Hideki Kato, Junji Ishida, Katsumasa Nagano, Kaori Honjo, Takeshi Sugaya, Norifumi Takeda, Fumihiro Sugiyama, Ken-Ichi Yagami, Toshiro Fujita, Masaomi Nangaku, Akiyoshi Fukamizu
  • Modeling formalin fixation and histological processing with ribonuclease A: effects of ethanol dehydration on reversal of formaldehyde cross-links
    Laboratory Investigation, Vol. aop, No. current.
    by Carol B Fowler, Timothy J O'Leary, Jeffrey T Mason
    posted by 1 person brianb
  • Role of the life span determinant P66shcA in ethanol-induced liver damage
    Laboratory Investigation, Vol. aop, No. current.
    by Osvaldo R Koch, Salvatore Fusco, Sofia C Ranieri, Giuseppe Maulucci, Paola Palozza, Luigi M Larocca, Amerys AM Cravero, Stella M Farre', Marco De Spirito, Tommaso Galeotti, Giovambattista Pani
  • Endothelial cells expressing Bcl-2 promotes tumor metastasis by enhancing tumor angiogenesis, blood vessel leakiness and tumor invasion
    Laboratory Investigation, Vol. aop, No. current.
    by Pawan Kumar, Yu Ning, Peter J Polverini
  • Chitinase 3-like-1 enhances bacterial adhesion to colonic epithelial cells through the interaction with bacterial chitin-binding protein
    Laboratory Investigation, Vol. aop, No. current.
    by Mayumi Kawada, Chun-Chuan Chen, Atsuko Arihiro, Katsuya Nagatani, Takeshi Watanabe, Emiko Mizoguchi
  • Helicobacter pylori invades the gastric mucosa and translocates to the gastric lymph nodes
    Laboratory Investigation, Vol. aop, No. current.
    by Takashi Ito, Daisuke Kobayashi, Keisuke Uchida, Tamiko Takemura, Sakae Nagaoka, Intetsu Kobayashi, Tetsuji Yokoyama, Ikuo Ishige, Yuki Ishige, Noriko Ishida, Asuka Furukawa, Hiroe Muraoka, Satoshi Ikeda, Masaki Sekine, Noboru Ando, Yoshimi Suzuki, Tetsuo Yamada, Takashige Suzuki, Yoshinobu Eishi
  • Induction of cytomegalovirus-infected labyrinthitis in newborn mice by lipopolysaccharide: a model for hearing loss in congenital CMV infection
    Laboratory Investigation, Vol. aop, No. current.
    by Li Li, Isao Kosugi, Gui-Ping Han, Hideya Kawasaki, Yoshifumi Arai, Tamotsu Takeshita, Yoshihiro Tsutsui
  • The origins of bladder cancer
    Laboratory Investigation, Vol. aop, No. current.
    by James M Crawford
  • Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy
    Laboratory Investigation, Vol. aop, No. current.
    by Tadeusz Majewski, Sangkyou Lee, Joon Jeong, Dong-Sup Yoon, Andrzej Kram, Mi-Sook Kim, Tomasz Tuziak, Jolanta Bondaruk, Sooyong Lee, Weon-Seo Park, Kuang S Tang, Woonbok Chung, Lanlan Shen, Saira S Ahmed, Dennis A Johnston, Barton H Grossman, Colin P Dinney, Jain-Hua Zhou, Alan R Harris, Carrie Snyder, Slawomir Filipek, Steven A Narod, Patrice Watson, Henry T Lynch, Adi Gazdar, Menashe Bar-Eli, Xifeng F Wu, David J Mcconkey, Keith Baggerly, Jean-Pierre Issa, William F Benedict, Steven E Scherer, Bogdan Czerniak
    posted by 1 person jyuh
  • Halofuginone upregulates the expression of heparanase in thioacetamide-induced liver fibrosis in rats
    Laboratory Investigation, Vol. aop, No. current.
    by Olga Ohayon, Nidal Mawasi, Anna Pevzner, Ana Tryvitz, Tsvia Gildor, Mark Pines, Marcos Rojkind, Melia Paizi, Gadi Spira
  • The acute cutaneous inflammatory response is attenuated in Slug-knockout mice
    Laboratory Investigation, Vol. aop, No. current.
    by Kimberly M Newkirk, Jason F Duncan, Erin M Brannick, Heather L Chandler, Allison E Parent, Donna F Kusewitt
  • Decoy oligodeoxynucleotide targeting activator protein-1 (AP-1) attenuates intestinal inflammation in murine experimental colitis
    Laboratory Investigation, Vol. aop, No. current.
    by Ichiro Moriyama, Shunji Ishihara, Azharul, Monowar MD Aziz, Yoshiyuki Mishima, Naoki Oshima, Chikara Kadota, Yasunori Kadowaki, Yuji Amano, Yoshikazu Kinoshita
  • Combined defects in epithelial and immunoregulatory factors exacerbate the pathogenesis of inflammation: mucin 2-interleukin 10-deficient mice
    Laboratory Investigation, Vol. aop, No. current.
    by Maria van der Sluis, Janneke Bouma, Audrey Vincent, Anna Velcich, Kermit L Carraway, Hans A Büller, Alexandra WC Einerhand, Johannes B van Goudoever, Isabelle Van Seuningen, Ingrid B Renes
  • Developmental reprogramming of IGF signaling and susceptibility to endometrial hyperplasia in the rat
    Laboratory Investigation, Vol. aop, No. current.
    by Adrienne S Mccampbell, Cheryl L Walker, Russell R Broaddus, Jennifer D Cook, Peter JA Davies
  • Everything you wanted to know about small RNA but were afraid to ask
    Laboratory Investigation, Vol. aop, No. current.
    by Scott D Boyd
    posted by 5 people microRNA heliopais balicea GustavoLacerda bootsy
  • Repeated exposure to acid and bile selectively induces colonic phenotype expression in a heterogeneous Barrett's epithelial cell line
    Laboratory Investigation, Vol. aop, No. current.
    by Manisha Bajpai, Jianying Liu, Xin Geng, Rhonda F Souza, Peter S Amenta, Kiron M Das
  • Regulation of scar formation by vascular endothelial growth factor
    Laboratory Investigation, Vol. aop, No. current.
    by Traci A Wilgus, Ahalia M Ferreira, Tatiana M Oberyszyn, Valerie K Bergdall, Luisa A Dipietro
  • The fibromatosis signature defines a robust stromal response in breast carcinoma
    Laboratory Investigation, Vol. aop, No. current.
    by Andrew H Beck, Inigo Espinosa, Blake C Gilks, Matt van de Rijn, Robert B West
  • Diabetic eNOS knockout mice develop distinct macro- and microvascular complications
    Laboratory Investigation, Vol. aop, No. current.
    by Sumathy Mohan, Robert L Reddick, Nicolas Musi, Diane A Horn, Bo Yan, Thomas J Prihoda, Mohan Natarajan, Sherry L Abboud-Werner
    posted by 1 person jyuh
  • The cancer stem cell hypothesis: in search of definitions, markers, and relevance
    Laboratory Investigation, Vol. aop, No. current.
    by Michail Shipitsin, Kornelia Polyak
  • The CD4+CD26− T-cell population in classical Hodgkin's lymphoma displays a distinctive regulatory T-cell profile
    Laboratory Investigation, Vol. aop, No. current.
    by Yue Ma, Lydia Visser, Tjasso Blokzijl, Geert Harms, Çiǧdem Atayar, Sibrand Poppema, Anke van den Berg
  • Motility-related actinin alpha-4 is associated with advanced and metastatic ovarian carcinoma
    Laboratory Investigation, Vol. aop, No. current.
    by Maria V Barbolina, Brian P Adley, David L Kelly, Angela J Fought, Denise M Scholtens, Lonnie D Shea, Sharon M Stack
  • Conjugated linoleic acids produced by Lactobacillus dissociates IKK-γ and Hsp90 complex in Helicobacter pylori-infected gastric epithelial cells
    Laboratory Investigation, Vol. aop, No. current.
    by Jung M Kim, Joo S Kim, Yeong J Kim, Yu K Oh, In Y Kim, Young J Chee, Joong S Han, Hyun C Jung
  • Involvement of hypoxia-triggered endoplasmic reticulum stress in outlet obstruction-induced apoptosis in the urinary bladder
    Laboratory Investigation, Vol. aop, No. current.
    by Norifumi Sawada, Jian Yao, Nobuhiko Hiramatsu, Kunihiro Hayakawa, Isao Araki, Masayuki Takeda, Masanori Kitamura
  • Expression of cell adhesion molecule 1 in malignant pleural mesothelioma as a cause of efficient adhesion and growth on mesothelium
    Laboratory Investigation, Vol. aop, No. current.
    by Akihiko Ito, Man Hagiyama, Takeshi Mimura, Masaki Matsumoto, Tomohiko Wakayama, Shoichi Iseki, Hiroshi Yokozaki, Morihito Okada
  • Metallothionein 1G acts as an oncosupressor in papillary thyroid carcinoma
    Laboratory Investigation, Vol. aop, No. current.
    by Cristina Ferrario, Paola Lavagni, Manuela Gariboldi, Claudia Miranda, Marco Losa, Loredana Cleris, Franca Formelli, Silvana Pilotti, Marco A Pierotti, Angela Greco
  • High-resolution array comparative genomic hybridization analysis of human bronchial and salivary adenoid cystic carcinoma
    Laboratory Investigation, Vol. aop, No. current.
    by Alain Bernheim, Saloua Toujani, Patrick Saulnier, Thomas Robert, Odile Casiraghi, Pierre Validire, Stéphane Temam, Philippe Menard, Philippe Dessen, Pierre Fouret
  • Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines
    Laboratory Investigation, Vol. aop, No. current.
    by Edurne Arriola, Caterina Marchio, David SP Tan, Suzanne C Drury, Maryou B Lambros, Rachael Natrajan, Socorro M Rodriguez-Pinilla, Alan Mackay, Narinder Tamber, Kerry Fenwick, Chris Jones, Mitch Dowsett, Alan Ashworth, Jorge S Reis-Filho
  • Activation of peroxisome proliferator-activated receptor-γ by curcumin blocks the signaling pathways for PDGF and EGF in hepatic stellate cells
    Laboratory Investigation, Vol. aop, No. current.
    by Jianguo Lin, Anping Chen
    posted by 1 person jyuh
  • Can Impact Factor data be trusted?
    Laboratory Investigation, Vol. aop, No. current.
    by Catherine M Ketcham, James M Crawford
  • Quantitative expression profiling of highly degraded RNA from formalin-fixed, paraffin-embedded breast tumor biopsies by oligonucleotide microarrays
    Laboratory Investigation, Vol. aop, No. current.
    by Maria Ravo, Margherita Mutarelli, Lorenzo Ferraro, Olì, Ornella Paris, Roberta Tarallo, Alessandra Vigilante, Daniela Cimino, Michele De Bortoli, Ernesto Nola, Luigi Cicatiello, Alessandro Weisz
    posted by 2 people jyuh jfr
  • MKK3 signalling plays an essential role in leukocyte-mediated pancreatic injury in the multiple low-dose streptozotocin model
    Laboratory Investigation, Vol. aop, No. current.
    by Kyoichi Fukuda, Greg H Tesch, Felicia Y Yap, Josephine M Forbes, Richard A Flavell, Roger J Davis, David J Nikolic-Paterson
  • Angiogenic heterogeneity in head and neck squamous cell carcinoma: biological and therapeutic implications
    Laboratory Investigation, Vol. aop, No. current.
    by Rifat Hasina, Mark E Whipple, Leslie E Martin, Winston P Kuo, Lucila Ohno-Machado, Mark W Lingen
  • A new tumor-specific variant of GRP78 as target for antibody-based therapy
    Laboratory Investigation, Vol. aop, No. current.
    by Nicole Rauschert, Stephanie Brändlein, Elisabeth Holzinger, Frank Hensel, Hans-Konrad Müller-Hermelink, Peter H Vollmers
  • Potential utility of xenobiotic mitogens in the context of liver regeneration in the elderly and living-related transplantation
    Laboratory Investigation, Vol. aop, No. current.
    by Amedeo Columbano, Michela Simbula, Monica Pibiri, Andrea Perra, Adolfo Pisanu, Alessandro Uccheddu, Giovanna M Ledda-Columbano
  • High-resolution optical coherence tomography imaging of the living kidney
    Laboratory Investigation, Vol. aop, No. current.
    by Peter M Andrews, Yu Chen, Maristela L Onozato, Shu-Wei Huang, Desmond C Adler, Robert A Huber, James Jiang, Scott E Barry, Alex E Cable, James G Fujimoto
  • Nestin expression in repopulating mesangial cells promotes their proliferation
    Laboratory Investigation, Vol. aop, No. current.
    by Christoph Daniel, Heinz Albrecht, Andrea Lüdke, Christian Hugo
    posted by 1 person jyuh
  • Impaired placental neovascularization in mice with pregnancy-associated hypertension
    Laboratory Investigation, Vol. aop, No. current.
    by Mitsuko Furuya, Junji Ishida, Saki Inaba, Yoshitoshi Kasuya, Sadao Kimura, Ryoichi Nemori, Akiyoshi Fukamizu
  • Caveolin-3 T78M and T78K missense mutations lead to different phenotypes in vivo and in vitro
    Laboratory Investigation, Vol. aop, No. current.
    by Monica Traverso, Elisabetta Gazzerro, Stefania Assereto, Federica Sotgia, Roberta Biancheri, Silvia Stringara, Laura Giberti, Marina Pedemonte, Xiabo Wang, Sara Scapolan, Elisabetta Pasquini, Maria A Donati, Federico Zara, Michael P Lisanti, Claudio Bruno, Carlo Minetti
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