Sat, 26 Jul 2008 08:37:02 BST CiteULike: dep Fujii http://www.citeulike.org/user/dep/author/Fujii CiteULike.org en-gb Copyright © 2004-2008 citeulike.org http://www.citeulike.org/user/dep/article/2188656 <i>Science, Vol. 301, No. 5637. (29 August 2003), pp. 1246-1249.</i><br /><br />Complex biological systems such as human language and the genetic code are characterized by explicit markers at the beginning and end of functional sequences. We report here that macaque prefrontal cortical neurons exhibit phasic peaks of spike activity that occur at the beginning and endpoint of sequential oculomotor saccade performance and have the properties of dynamic start- and end-state encoders accompanying responses to sequential actions. Sequence bounding may thus reflect a general mechanism for encoding biological information. Representation of action sequence boundaries by macaque prefrontal cortical neurons. N Fujii AM Graybiel doi:10.1126/science.1086872 Science, Vol. 301, No. 5637. (29 August 2003), pp. 1246-1249. 2008-01-02T16:32:52-00:00 2003 Science 1095-9203 301 5637 1246 1249 action macaques pfc representation sequencce