Wed, 20 Aug 2008 22:08:07 BST CiteULike: dep exercise http://www.citeulike.org/user/dep/tag/exercise CiteULike.org en-gb Copyright © 2004-2008 citeulike.org http://www.citeulike.org/user/dep/article/1365895 <i>J Endocrinol, Vol. 193, No. 2. (1 May 2007), pp. 251-258.</i><br /><br />This study investigated the acute effects of exercise on the postprandial levels of appetite-related hormones and metabolites, energy intake (EI) and subjective measures of appetite. Ghrelin, polypeptide YY (PYY), glucagon-like peptide-1 (GLP-1) and pancreatic polypeptide (PP) were measured in the fasting state and postprandially in 12 healthy, normal-weight volunteers (six males and six females) using a randomised crossover design. One hour after a standardised breakfast, subjects either cycled for 60 min at 65% of their maximal heart rate or rested. Subjective appetite was assessed throughout the study using visual analogue scales and subsequent EI at a buffet meal was measured at the end (3-h post-breakfast and 1-h post-exercise). Exercise significantly increased mean PYY, GLP-1 and PP levels, and this effect was maintained during the post-exercise period for GLP-1 and PP. No significant effect of exercise was observed on postprandial levels of ghrelin. During the exercise period, hunger scores were significantly decreased; however, this effect disappeared in the post-exercise period. Exercise significantly increased subsequent absolute EI, but produced a significant decrease in relative EI after accounting for the energy expended during exercise. Hunger scores and PYY, GLP-1 and PP levels showed an inverse temporal pattern during the 1-h exercise/control intervention. In conclusion, acute exercise, of moderate intensity, temporarily decreased hunger sensations and was able to produce a short-term negative energy balance. This impact on appetite and subsequent energy homeostasis was not explained by changes in postprandial levels of ghrelin; however, exercise-induced anorexia' may potentially be linked to increased PYY, GLP-1 and PP levels. 10.1677/JOE-06-0030 Effects of exercise on gut peptides, energy intake and appetite Catia Martins Linda Morgan Stephen Bloom Denise Robertson doi:10.1677/JOE-06-0030 J Endocrinol, Vol. 193, No. 2. (1 May 2007), pp. 251-258. 2007-06-05T17:10:29-00:00 2007 J Endocrinol 193 2 251 258 diet exercise metabolism