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Ключевое слово activity_profile [12 articles]

Recent papers classified by the tag activity_profile.
  • Do structurally similar molecules have similar biological activity?
    J Med Chem, Vol. 45, No. 19. (12 September 2002), pp. 4350-4358.
    by YC Martin, JL Kofron, LM Traphagen
    posted to activity_profile chemical p similarity by kuhn on 2006-09-06 08:08:57 as ** along with 1 person and 2 groups sangeetha Bioinformatics insilicodrug
  • The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.
    Science, Vol. 313, No. 5795. (29 September 2006), pp. 1929-1935.
    by J Lamb, ED Crawford, D Peck, JW Modell, IC Blat, MJ Wrobel, J Lerner, JP Brunet, A Subramanian, KN Ross, M Reich, H Hieronymus, G Wei, SA Armstrong, SJ Haggarty, PA Clemons, R Wei, SA Carr, ES Lander, TR Golub
    posted to activity_profile bioassay chemical drug microarray by kuhn on 2006-10-02 09:35:58 as ** along with 22 people and 9 groups dansullivanblk BragilMassoud jyuh jfr yas balajis marcius lhonigberg neveaire kengg ealloza koller mlovell jdiggans ezra jeremymiller frohike massivemayhem lp2 pablomendes jdiezperezj askrajiv Biostatistics Computational-Genomics Bioinformatics Neuroscience T_lab BioinfoCIPF SGU-CIPF GeschwindLab Plantandetc
  • Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors
    Nat Biotech, Vol. 25, No. 9. (2007), pp. 1035-1044.
    by Marcus Bantscheff, Dirk Eberhard, Yann Abraham, Sonja Bastuck, Markus Boesche, Scott Hobson, Toby Mathieson, Jessica Perrin, Manfred Raida, Christina Rau, Valerie Reader, Gavain Sweetman, Andreas Bauer, Tewis Bouwmeester, Carsten Hopf, Ulrich Kruse, Gitte Neubauer, Nigel Ramsden, Jens Rick, Bernhard Kuster, Gerard Drewes
    posted to activity_profile drug kinase by kuhn on 2007-10-23 13:54:07 as ** along with 2 people jyuh apostola
  • The selectivity of protein kinase inhibitors: a further update.
    Biochem J, Vol. 408, No. 3. (15 December 2007), pp. 297-315.
    by J Bain, L Plater, M Elliott, N Shpiro, CJ Hastie, H McLauchlan, I Klevernic, JS Arthur, DR Alessi, P Cohen
    posted to activity_profile kinase by kuhn on 2007-12-20 14:38:09 as ** along with 2 people jyuh pbarker
  • Analysis of System Structure-Function Relationships
    ChemMedChem, Vol. 2, No. 12. (2007), pp. 1774-1782.
    by Anton F Fliri, William T Loging, Robert A Volkmann
    posted to activity_profile biospectra side_effects similarity by kuhn on 2008-01-18 13:21:14 as **
  • New uses for old drugs
    Nature, Vol. 448, No. 7154. (08 August 2007), pp. 645-646.
    by Curtis R Chong, David J Sullivan
    posted to activity_profile drug drugdiscovery by kuhn on 2007-11-21 15:58:20 as **
  • From Astemizole to a Novel Hit Series of Small-Molecule Somatostatin 5 Receptor Antagonists via GPCR Affinity Profiling
    J. Med. Chem., Vol. 50, No. 25. (13 December 2007), pp. 6295-6298.
    by Wolfgang Guba, Luke G Green, Rainer E Martin, Olivier Roche, Nicole Kratochwil, Harald Mauser, Caterina Bissantz, Andreas Christ, Martin Stahl
    posted to activity_profile drugdiscovery gpcr by kuhn on 2008-01-11 13:24:18 as **
  • Biological spectra analysis: Linking biological activity profiles to molecular structure
    PNAS, Vol. 102, No. 2. (11 January 2005), pp. 261-266.
    by Anton F Fliri, William T Loging, Peter F Thadeio, Robert A Volkmann
    posted to activity_profile biospectra drug structure by kuhn on 2006-02-14 12:55:16 as **
  • Global mapping of pharmacological space
    Nature Biotechnology, Vol. 24, No. 7. (13 July 2006), pp. 805-815.
    by Gaia V Paolini, Richard HB Shapland, Willem P van Hoorn, Jonathan S Mason, Andrew L Hopkins
    posted to activity_profile drug networks promiscuity ruleof5 by kuhn on 2006-07-17 09:44:52 as read along with 7 people and 1 group Yanno BragilMassoud jyuh bicko caporaso allmensch jerome_ucsf_slb biomedical-nlp
  • Deriving knowledge through data mining high-throughput screening data.
    J Med Chem, Vol. 47, No. 25. (2 December 2004), pp. 6373-6383.
    by DJ Diller, DW Hobbs
    posted to activity_profile bioassay chemical by kuhn on 2006-09-06 09:29:14 as **
  • Integrating high-content screening and ligand-target prediction to identify mechanism of action.
    Nat Chem Biol, Vol. 4, No. 1. (January 2008), pp. 59-68.
    by DW Young, A Bender, J Hoyt, E McWhinnie, GW Chirn, CY Tao, JA Tallarico, M Labow, JL Jenkins, TJ Mitchison, Y Feng
    posted to activity_profile drugdiscovery screening by kuhn on 2007-12-20 14:39:42 as ** along with 3 people Yanno jyuh kengg
  • A priori inference of cross reactivity for drug-targeted kinases.
    J Med Chem, Vol. 49, No. 11. (1 June 2006), pp. 3092-3100.
    by A Fernandez, S Maddipati
    posted to activity_profile drug kinase by kuhn on 2007-10-23 13:50:50 as ** along with 2 people BragilMassoud tjimenez
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