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Ключевое слово ccr5 [170 articles]

Recent papers classified by the tag ccr5.
  • Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cellâdendritic cell interaction
    Nature, Vol. 440, No. 7086., pp. 890-895.
    by Flora Castellino, Alex Y Huang, Grã©goire Altan-Bonnet, Sabine Stoll, Clemens Scheinecker, Ronald N Germain
    posted to ccr5 cells dc mip1s t by zukeboy on 2006-05-03 14:38:06 as read
  • Coordinate Expression of CC Chemokine Ligand 5, Granulysin, and Perforin in CD8+ T Cells Provides a Host Defense Mechanism against Mycobacterium tuberculosis
    J Immunol, Vol. 175, No. 11. (1 December 2005), pp. 7474-7483.
    by Frank Stegelmann, Max Bastian, Kay Swoboda, Rauf Bhat, Viviane Kiessler, Alan M Krensky, Martin Roellinghoff, Robert L Modlin, Steffen Stenger
    posted to ccr5 secretion by zukeboy on 2006-01-31 17:29:48 as ** along with 1 person jjray
  • The Case for Selection at CCR5-Delta32.
    PLoS Biol, Vol. 3, No. 11. (1 November 2005)
    by Pardis C C Sabeti, Emily Walsh, Steve F F Schaffner, Patrick Varilly, Ben Fry, Holli B B Hutcheson, Mike Cullen, Tarjei S S Mikkelsen, Jessica Roy, Nick Patterson, Richard Cooper, David Reich, David Altshuler, Stephen Oʼbrien, Eric S S Lander
    posted to ccr5 by zukeboy on 2005-11-01 13:04:47 as ** along with 2 people and 2 groups stevanspringer indigoviolet EisenLab FAB-lab
  • CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms
    Nature Immunology, Vol. 8, No. 12. (21 October 2007), pp. 1324-1336.
    by Matthew J Dolan, Hemant Kulkarni, Jose F Camargo, Weijing He, Alison Smith, Juan-Manuel Anaya, Toshiyuki Miura, Frederick M Hecht, Manju Mamtani, Florencia Pereyra, Vincent Marconi, Andrea Mangano, Luisa Sen, Rosa Bologna, Robert A Clark, Stephanie A Anderson, Judith Delmar, Robert J O'Connell, Andrew Lloyd, Jeffrey Martin, Seema S Ahuja, Brian K Agan, Bruce D Walker, Steven G Deeks, Sunil K Ahuja
    posted to ccr5 hiv immunology by xingxu on 2007-11-29 03:37:33 as ** along with 1 person shimi002
  • Structural and dynamical changes in an alpha-subunit of a heterotrimeric G protein along the activation pathway.
    Proc Natl Acad Sci U S A (19 October 2006)
    by Ned Van Eps, William M M Oldham, Heidi E E Hamm, Wayne L L Hubbell
    posted to amine ccr5 disease by xdeupi on 2006-10-27 12:10:34 as ** along with 1 group LabCompMed
  • The chemokine and chemokine receptor superfamilies and their molecular evolution
    Genome Biology, Vol. 7 (29 December 2006), 243.
    by Albert Zlotnik, Osamu Yoshie, Hisayuki Nomiyama
    posted to review genome evolution cxcr1 chemokine ccr5 by xdeupi on 2007-02-06 09:22:39 as ** along with 1 group LabCompMed
  • Activation of CCR5 by chemokines involves an aromatic cluster between transmembrane helices 2 and 3.
    J Biol Chem, Vol. 278, No. 3. (17 January 2003), pp. 1892-1903.
    by C Govaerts, A Bondue, JY Springael, M Olivella, X Deupi, E Le Poul, SJ Wodak, M Parmentier, L Pardo, C Blanpain
    posted to activation ccr5 helix tm2 tm3 by xdeupi on 2005-10-25 03:15:57 as read along with 1 person and 1 group tkershaw LabCompMed
  • New concepts in drug discovery: collateral efficacy and permissive antagonism.
    Nat Rev Drug Discov, Vol. 4, No. 11. (November 2005), pp. 919-927.
    by T Kenakin
    posted to activation agonist ccr5 gpcr ligands by xdeupi on 2005-11-04 21:57:24 as ** along with 1 group LabCompMed
  • The TXP motif in the second transmembrane helix of CCR5. A structural determinant of chemokine-induced activation.
    J Biol Chem, Vol. 276, No. 16. (20 April 2001), pp. 13217-13225.
    by C Govaerts, C Blanpain, X Deupi, S Ballet, JA Ballesteros, SJ Wodak, G Vassart, L Pardo, M Parmentier
    posted to ccr5 helix tm2 transmembrane txp by xdeupi on 2005-10-25 03:18:46 as ** along with 1 person and 1 group tkershaw LabCompMed
  • Chemokine receptor CCR5 is not required for development of experimental autoimmune gastritis.
    Clinical immunology (Orlando, Fla.), Vol. 109, No. 2. (November 2003), pp. 238-247.
    by J Field, AC Marshall, P J Hertzog, TN Wells, F Alderuccio, BH Toh
    posted to perniciousanemia ccr5 autoantibody by vplagnol on 2008-09-18 00:53:27 as **
  • The second extracellular loop of CCR5 is the major determinant of ligand specificity.
    J Biol Chem, Vol. 272, No. 40. (3 October 1997), pp. 24934-24941.
    by M Samson, G LaRosa, F Libert, P Paindavoine, M Detheux, G Vassart, M Parmentier
    posted to ccr5 by Vaccine on 2005-12-02 18:18:04 as read along with 1 person tkershaw
  • Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene.
    Nature, Vol. 382, No. 6593. (22 August 1996), pp. 722-725.
    by M Samson, F Libert, BJ Doranz, J Rucker, C Liesnard, CM Farber, S Saragosti, C Lapoumeroulie, J Cognaux, C Forceille, G Muyldermans, C Verhofstede, G Burtonboy, M Georges, T Imai, S Rana, Y Yi, RJ Smyth, RG Collman, RW Doms, G Vassart, M Parmentier
    posted to ccr5 by Vaccine on 2005-12-02 18:17:28 as read along with 1 person tkershaw
  • Extracellular cysteines of CCR5 are required for chemokine binding, but dispensable for HIV-1 coreceptor activity.
    J Biol Chem, Vol. 274, No. 27. (2 July 1999), pp. 18902-18908.
    by C Blanpain, B Lee, J Vakili, BJ Doranz, C Govaerts, I Migeotte, M Sharron, V Dupriez, G Vassart, RW Doms, M Parmentier
    posted to ccr5 by Vaccine on 2005-12-02 18:15:20 as read along with 1 person tkershaw
  • Mycobacterium tuberculosis upregulates coreceptors CCR5 and CXCR4 while HIV modulates CD14 favoring concurrent infection.
    AIDS Res Hum Retroviruses, Vol. 22, No. 1. (January 2006), pp. 45-51.
    by AG Rosas-Taraco, AY Arce-Mendoza, G Caballero-Olín, MC Salinas-Carmona
    posted to ccr5 cd14 cxcr4 hiv mycobacterium tuberculosis by tore on 2006-11-16 16:17:03 as ***** along with 1 person HugoMarcelo
  • Chemokine-induced phosphorylation of CC chemokine receptor 5 (CCR5).
    J Leukoc Biol, Vol. 65, No. 3. (March 1999), pp. 281-285.
    by H Olbrich, AE Proudfoot, M Oppermann
    posted to ccr5 oppermann review trafficking by tkershaw on 2005-10-25 17:01:51 as ** along with 1 person Silene
  • Molecular modeling and site-directed mutagenesis of CCR5 reveal residues critical for chemokine binding and signal transduction.
    European journal of immunology, Vol. 30, No. 1. (January 2000), pp. 164-173.
    by N Zhou, Z Luo, JW Hall, J Luo, X Han, Z Huang
    posted to ccr5 intro by tkershaw on 2008-06-07 12:27:48 as **
  • CCR5 and HIV Infection
    Receptors and Channels (January 2002), pp. 19-31.
    by C Blanpain, F Libert, G Vassart, M Parmentier
    posted to ccr5 intro by tkershaw on 2008-06-07 11:47:00 as **
  • Identification of a major co-receptor for primary isolates of HIV-1
    Nature, Vol. 381, No. 6584. (20 June 1996), pp. 661-666.
    by Hongkui Deng, Rong Liu, Wilfried Ellmeier, Sunny Choe, Derya Unutmaz, Michael Burkhart, Paola D Marzio, Shoshana Marmon, Richard E Sutton, Mark C Hill, Craig B Davis, Stephen C Peiper, Thomas J Schall, Dan R Littman, Nathaniel R Landau
    posted to ccr5 hiv by tkershaw on 2008-07-16 11:05:36 as **
  • HIV and the chemokine system: 10 years later
    The EMBO Journal, Vol. aop, No. current. (26 January 2006)
    by Paolo Lusso
    posted to ccr5 cxcr4 hiv review by tkershaw on 2006-01-30 08:52:56 as ** along with 1 person gokhan
  • Pathways for internalization and recycling of the chemokine receptor CCR5.
    Blood, Vol. 99, No. 3. (1 February 2002), pp. 785-791.
    by A Mueller, E Kelly, PG Strange
    posted to ccr5 cho by tkershaw on 2008-06-06 22:01:18 as **
  • Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein.
    The Journal of biological chemistry, Vol. 274, No. 49. (3 December 1999), pp. 34719-34727.
    by C Blanpain, BJ Doranz, J Vakili, J Rucker, C Govaerts, SS Baik, O Lorthioir, I Migeotte, F Libert, F Baleux, G Vassart, RW Doms, M Parmentier
    posted to ccr5 hiv intro by tkershaw on 2008-06-07 12:24:37 as **
  • Interleukin-8-mediated Heterologous Receptor Internalization Provides Resistance to HIV-1 Infectivity. ROLE OF SIGNAL STRENGTH AND RECEPTOR DESENSITIZATION
    J. Biol. Chem., Vol. 278, No. 18. (25 April 2003), pp. 15867-15873.
    by Ricardo M Richardson, Kenzo Tokunaga, Robin Marjoram, Tetsutaro Sata, Ralph Snyderman
    posted to ccr5 endocytosis hiv by tkershaw on 2008-06-07 16:07:57 as **
  • Reciprocal Desensitization of CCR5 and CD4 Is Mediated by IL-16 and Macrophage-Inflammatory Protein-1beta, Respectively
    J Immunol, Vol. 163, No. 6. (15 September 1999), pp. 3123-3130.
    by Vallen M Mashikian, TC Ryan, A Seman, W Brazer, DM Center, WW Cruikshank
    posted to ccr5 cd4 by tkershaw on 2008-06-07 16:10:59 as **
  • Cutting Edge: Vasoactive Intestinal Peptide Acts as a Potent Suppressor of Inflammation In Vivo by Trans-Deactivating Chemokine Receptors
    J Immunol, Vol. 171, No. 10. (15 November 2003), pp. 4990-4994.
    by Michael C Grimm, Rosie Newman, Zeenath Hassim, Natalia Cuan, Susan J Connor, Yingying Le, Ji M Wang, Joost J Oppenheim, Andrew R Lloyd
    posted to ccr5 by tkershaw on 2008-06-07 16:11:59 as **
  • Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus–cell fusion
    Nature (30 October 2005)
    by Ronald S Veazey, Per J Klasse, Susan M Schader, Qinxue Hu, Thomas J Ketas, Min Lu, Preston A Marx, Jason Dufour, Richard J Colonno, Robin J Shattock, Martin S Springer, John P Moore
    posted to ccr5 hiv interest transmission by tkershaw on 2005-10-31 10:39:42 as read along with 1 person Vaccine
  • Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population.
    J. Virol., Vol. 66, No. 3. (1 March 1992), pp. 1354-1360.
    by H Schuitemaker, M Koot, NA Kootstra, MW Dercksen, RE de Goede, RP van Steenwijk, JM Lange, JK Schattenkerk, F Miedema, M Tersmette
    posted to ccr5 hiv by tkershaw on 2008-07-18 12:36:27 as **
  • Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease.
    Annual review of immunology, Vol. 17 (1999), pp. 657-700.
    by EA Berger, PM Murphy, JM Farber
    posted to ccr5 hiv by tkershaw on 2008-06-07 11:35:26 as **
  • Long-lasting CCR5 internalization by antibodies in a subset of long-term nonprogressors: a possible protective effect against disease progression.
    Blood, Vol. 107, No. 12. (15 June 2006), pp. 4825-4833.
    by C Pastori, B Weiser, C Barassi, C Uberti-Foppa, S Ghezzi, R Longhi, G Calori, H Burger, K Kemal, G Poli, A Lazzarin, L Lopalco
    posted to ccr5 interest by tkershaw on 2006-08-16 09:29:34 as **
  • Analysis of Binding Sites for the New Small-Molecule CCR5 Antagonist TAK-220 on Human CCR5.
    Antimicrob Agents Chemother, Vol. 49, No. 11. (November 2005), pp. 4708-4715.
    by M Nishikawa, K Takashima, T Nishi, RA Furuta, N Kanzaki, Y Yamamoto, J Fujisawa
    posted to antagonist ccr5 by tkershaw on 2005-10-31 09:19:24 as *
  • Macrophage Inflammatory Protein-1beta Induces Migration and Activation of Human Thymocytes
    Blood, Vol. 91, No. 8. (15 April 1998), pp. 2905-2913.
    by Daniel J Dairaghi, Karin Franz-Bacon, Eleni Callas, James Cupp, Thomas J Schall, Susan A Tamraz, Stefen A Boehme, Naomi Taylor, Kevin B Bacon
    posted to ccr5 chemotaxis signalling by tkershaw on 2008-06-07 13:40:06 as **
  • Endocytosis and recycling of the HIV coreceptor CCR5.
    J Cell Biol, Vol. 151, No. 6. (11 December 2000), pp. 1281-1294.
    by N Signoret, A Pelchen-Matthews, M Mack, AE Proudfoot, M Marsh
    posted to ccr5 nath by tkershaw on 2005-10-18 09:32:55 as read
  • Maraviroc (UK-427,857), a Potent, Orally Bioavailable, and Selective Small-Molecule Inhibitor of Chemokine Receptor CCR5 with Broad-Spectrum Anti-Human Immunodeficiency Virus Type 1 Activity.
    Antimicrob Agents Chemother, Vol. 49, No. 11. (November 2005), pp. 4721-4732.
    by P Dorr, M Westby, S Dobbs, P Griffin, B Irvine, M Macartney, J Mori, G Rickett, C Smith-Burchnell, C Napier, R Webster, D Armour, D Price, B Stammen, A Wood, M Perros
    posted to ccr5 hiv therapy by tkershaw on 2005-10-31 09:18:36 as read
  • Molecular cloning and functional expression of a new human CC-chemokine receptor gene.
    Biochemistry, Vol. 35, No. 11. (19 March 1996), pp. 3362-3367.
    by M Samson, O Labbe, C Mollereau, G Vassart, M Parmentier
    posted to ccr5 intro methods by tkershaw on 2008-06-07 11:55:51 as **
  • RANTES Activates Jak2 and Jak3 to Regulate Engagement of Multiple Signaling Pathways in T Cells
    J. Biol. Chem., Vol. 276, No. 14. (30 March 2001), pp. 11427-11431.
    by Mark Wong, Shahab Uddin, Beata Majchrzak, Tai Huynh, Amanda E Proudfoot, Leonidas C Platanias, Eleanor N Fish
    posted to ccr5 chemotaxis signalling by tkershaw on 2008-06-07 13:43:28 as **
  • RANTES induces tyrosine kinase activity of stably complexed p125FAK and ZAP-70 in human T cells.
    The Journal of experimental medicine, Vol. 184, No. 3. (1 September 1996), pp. 873-882.
    by KB Bacon, MC Szabo, H Yssel, JB Bolen, TJ Schall
    posted to ccr5 chemotaxis signalling by tkershaw on 2008-06-07 13:37:41 as **
  • Chemokine receptors.
    Cytokine Growth Factor Rev, Vol. 12, No. 4. (December 2001), pp. 313-335.
    by R Horuk
    posted to ccr5 chemokine_receptor cxcr4 review by tkershaw on 2005-10-18 10:41:38 as read
  • The current status of, and challenges in, the development of CCR5 inhibitors as therapeutics for HIV-1 infection.
    Curr Opin Pharmacol, Vol. 4, No. 5. (October 2004), pp. 447-452.
    by K Maeda, H Nakata, H Ogata, Y Koh, T Miyakawa, H Mitsuya
    posted to ccr5 gsk140 hiv review therapy by tkershaw on 2005-10-18 10:27:04 as read
  • pH-independent endocytic cycling of the chemokine receptor CCR5.
    Traffic, Vol. 5, No. 7. (July 2004), pp. 529-543.
    by N Signoret, T Christophe, M Oppermann, M Marsh
    posted to ccr5 nath by tkershaw on 2005-10-17 10:34:16 as read along with 1 person Silene
  • Receptors induce chemotaxis by releasing the beta gamma subunit of Gi, not by activating Gq or Gs
    PNAS, Vol. 94, No. 26. (23 December 1997), pp. 14489-14494.
    by Enid R Neptune, Henry R Bourne
    posted to ccr5 chemotaxis signalling by tkershaw on 2008-06-07 13:25:36 as ** along with 1 person and 2 groups rhem1224 TCR_Signaling SysbioMPI-TCells
  • Naturally Occurring CCR5 Extracellular and Transmembrane Domain Variants Affect HIV-1 Co-receptor and Ligand Binding Function
    J. Biol. Chem., Vol. 274, No. 23. (4 June 1999), pp. 16228-16234.
    by Zack OM  Howard, Aiko-Konno Shirakawa, Jim A Turpin, Andrew Maynard, Gregory J Tobin, Mary Carrington, Joost J Oppenheim, Michael Dean
    posted to ccr5 intro by tkershaw on 2008-06-07 12:34:24 as **
  • Variants of CCR5, which are permissive for HIV-1 infection, show distinct functional responses to CCL3, CCL4 and CCL5
    Genes and Immunity, Vol. aop, No. current.
    by HF Dong, K Wigmore, MN Carrington, M Dean, JA Turpin, OMZ Howard,
    posted to ccr5 by tkershaw on 2005-12-19 08:35:20 as *****
  • CXCR4/CCR5 Down-modulation and Chemotaxis Are Regulated by the Proteasome Pathway
    J. Biol. Chem., Vol. 277, No. 20. (10 May 2002), pp. 18111-18117.
    by Aaron Z Fernandis, Rama P Cherla, Rebecca D Chernock, Ramesh K Ganju
    posted to ccr5 by tkershaw on 2008-06-07 17:40:20 as **
  • Sialylated O-glycans and sulfated tyrosines in the NH2-terminal domain of CC chemokine receptor 5 contribute to high affinity binding of chemokines.
    The Journal of experimental medicine, Vol. 194, No. 11. (3 December 2001), pp. 1661-1673.
    by N Bannert, S Craig, M Farzan, D Sogah, NV Santo, H Choe, J Sodroski
    posted to ccr5 intro ptm by tkershaw on 2008-06-07 12:41:46 as **
  • Mechanisms of internalization and recycling of the chemokine receptor, CCR5.
    Eur J Biochem, Vol. 271, No. 2. (January 2004), pp. 243-252.
    by A Mueller, PG Strange
    posted to ccr5 trafficking by tkershaw on 2006-01-04 09:54:41 as read
  • Co-receptor use by HIV and inhibition of HIV infection by chemokine receptor ligands.
    Immunol Rev, Vol. 177 (October 2000), pp. 112-126.
    by G Simmons, JD Reeves, S Hibbitts, JT Stine, PW Gray, AE Proudfoot, PR Clapham
    posted to ccr5 chemokine_receptor hiv by tkershaw on 2005-11-14 16:14:52 as *
  • What's New in HIV/AIDS? Chemokine Receptor Antagonists: A New Era of HIV Therapy?
    Infection, Vol. 33, No. 5-6. (October 2005), pp. 408-410.
    by B Jülg, FD Goebel
    posted to ccr5 cxcr4 hiv therapy by tkershaw on 2005-11-02 09:39:55 as read
  • Characterization of RANTES- and aminooxypentane-RANTES-triggered desensitization signals reveals differences in recruitment of the G protein-coupled receptor complex.
    Journal of immunology (Baltimore, Md. : 1950), Vol. 163, No. 6. (15 September 1999), pp. 3037-3044.
    by AJ Vila-Coro, M Mellado, A Martín de Ana, C Martínez-A, JM Rodríguez-Frade
    posted to aop-rantes ccr5 phosphorylation by tkershaw on 2008-06-07 17:28:23 as **
  • Molecular mechanism of desensitization of the chemokine receptor CCR-5: receptor signaling and internalization are dissociable from its role as an HIV-1 co-receptor.
    EMBO J, Vol. 16, No. 15. (1 August 1997), pp. 4606-4616.
    by I Aramori, SS Ferguson, PD Bieniasz, J Zhang, B Cullen, MG Cullen
    posted to ccr5 signalling by tkershaw on 2005-11-14 16:04:37 as *
  • Cutting Edge: Role of C-C Chemokine Receptor 5 in Organ-Specific and Innate Immunity to Cryptococcus neoformans
    J Immunol, Vol. 163, No. 9. (1 November 1999), pp. 4642-4646.
    by Gary B Huffnagle, Lisa K Mcneil, Roderick A Mcdonald, Juneann W Murphy, Galen B Toews, Nobuyo Maeda, William A Kuziel
    posted to ccr5 by tkershaw on 2008-07-18 12:11:01 as **
  • Structure Modeling of the Chemokine Receptor CCR5: Implications for Ligand Binding and Selectivity
    Biophys. J., Vol. 83, No. 6. (1 December 2002), pp. 3012-3031.
    by Germana M Paterlini
    posted to ccr5 intro by tkershaw on 2008-06-07 12:14:23 as **
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