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Ключевое слово cyclophosphamide [40 articles]

Recent papers classified by the tag cyclophosphamide.
  • Involvement of human glutathione S-transferase isoenzymes in the conjugation of cyclophosphamide metabolites with glutathione.
    Cancer Res, Vol. 54, No. 23. (1 December 1994), pp. 6215-6220.
    by HA Dirven, B van Ommen, PJ van Bladeren
    posted to alkylation cyclophosphamide detoxification glutathione glutathione-s-transferase human phosphoramide_mustard by uz_labu_laimi on 2007-03-22 17:41:38 as **
  • Spermiogenic germ cell phase-specific DNA damage following cyclophosphamide exposure.
    J Androl, Vol. 25, No. 3. (n 2004), pp. 354-362.
    by AM Codrington, BF Hales, B Robaire
    posted to comet_assay cyclophosphamide dna_damage spermatogenesis spermiogenesis by uz_labu_laimi on 2007-03-27 19:16:07 as ***
  • Cyclophosphamide-induced depression of the antioxidant defense mechanisms of the lung.
    Exp Lung Res, Vol. 8, No. 2-3. (1985), pp. 153-165.
    by JM Patel, ER Block
    posted to acrolein antioxidant cyclophosphamide depression_of_antioxidant_defense lung oxidative_stress by uz_labu_laimi on 2007-03-30 05:39:02 as **
  • A time-course study of chronic paternal cyclophosphamide treatment in rats: effects on pregnancy outcome and the male reproductive and hematologic systems.
    Biol Reprod, Vol. 37, No. 2. (September 1987), pp. 317-326.
    by JM Trasler, BF Hales, B Robaire
    posted to chronic_exposure cyclophosphamide haematologic_system male_reproductive_system progeny_outcome rat by uz_labu_laimi on 2007-08-27 18:26:51 as ***
  • Cyclophosphamide: Review of its mutagenicity for an assessment of potential germ cell risks
    Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, Vol. 330, No. 1-2. (August 1995), pp. 115-181.
    by Diana Anderson, Jack B Bishop, Colin R Garner, Patricia Ostrosky-Wegman, Paul B Selby
    posted to cyclophosphamide dna_damage germ_cell mutagenicity by uz_labu_laimi on 2007-04-02 14:59:22 as **
  • Transcription-terminating lesions induced by bifunctional alkylating agents in vitro.
    Carcinogenesis, Vol. 10, No. 7. (July 1989), pp. 1307-1314.
    by RO Pieper, BW Futscher, LC Erickson
    posted to alkylating_agent cyclophosphamide dna_damage in_vitro transcription by uz_labu_laimi on 2007-04-02 15:30:44 as **
  • Numerical Chromosomal Abnormalities in Rat Epididymal Spermatozoa Following Chronic Cyclophosphamide Exposure
    Biol Reprod, Vol. 69, No. 4. (1 October 2003), pp. 1150-1157.
    by Tara S Barton, Andrew J Wyrobek, Francesca S Hill, Bernard Robaire, Barbara F Hales
    posted to chromosome cyclophosphamide disomy epididymal_spermatozoa rat spermatozoa by uz_labu_laimi on 2007-05-07 16:13:26 as read
  • Induction of apoptosis in the germ cells of adult male rats after exposure to cyclophosphamide
    Biol Reprod, Vol. 56, No. 6. (1 June 1997), pp. 1490-1497.
    by L Cai, Bf Hales, B Robaire
    posted to apoptosis cyclophosphamide male_germ_cells rat by uz_labu_laimi on 2007-05-09 23:37:54 as ***
  • Protective effect of ascorbic acid on cyclophosphamide- induced testicular gametogenic and androgenic disorders in male rats.
    Asian J Androl, Vol. 4, No. 3. (September 2002), pp. 201-207.
    by UB Das, M Mallick, JM Debnath, D Ghosh
    posted to androgen ascorbic_acid cyclophosphamide oxidative_stress rat testis testosterone by uz_labu_laimi on 2007-05-28 05:47:35 as ***
  • Chronic low dose cyclophosphamide treatment of adult male rats: effect on fertility, pregnancy outcome and progeny.
    Biol Reprod, Vol. 34, No. 2. (March 1986), pp. 275-283.
    by JM Trasler, BF Hales, B Robaire
    posted to cyclophosphamide fertility male-mediated paternal_exposure pregnancy_outcome progeny rat by uz_labu_laimi on 2007-03-27 19:01:40 as **
  • Cyclophosphamide resistance in medulloblastoma.
    Cancer Res, Vol. 52, No. 19. (1 October 1992), pp. 5373-5378.
    by HS Friedman, OM Colvin, SH Kaufmann, SM Ludeman, N Bullock, DD Bigner, OW Griffith
    posted to cyclophosphamide drug_resistance gamma-glutamyl_transpeptidase medulloblastoma by uz_labu_laimi on 2007-05-31 21:34:08 as *
  • Morphological changes in the testis and epididymis of rats treated with cyclophosphamide: a quantitative approach.
    Biol Reprod, Vol. 38, No. 2. (March 1988), pp. 463-479.
    by JM Trasler, L Hermo, B Robaire
    posted to cyclophosphamide epididymis male_germ_line morphology spermatogenesis testis by uz_labu_laimi on 2007-03-27 18:54:22 as ***
  • The stress response in gametes and embryos after paternal chemical exposures
    Toxicology and Applied Pharmacology, Vol. 207, No. 2, Supplement 1. (1 September 2005), pp. 514-520.
    by Barbara F Hales, Adriana Aguilar-Mahecha, Bernard Robaire
    posted to cyclophosphamide embryo gamete gene_expression male_germ_line paternal_exposure spermatozoa stress_response_genes by uz_labu_laimi on 2007-03-21 03:28:30 as **
  • DNA and the chromosome – varied targets for chemotherapy
    Cell & Chromosome, Vol. 3 (24 May 2004), 2.
    by Stephanie M Nelson, Lynnette R Ferguson, William A Denny
    posted to alkylating_agents chemotherapy cyclophosphamide dna_adduction dna_crosslinking dna_damage review by uz_labu_laimi on 2007-03-30 22:46:21 as **
  • Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex.
    Proc Natl Acad Sci U S A, Vol. 102, No. 9. (1 March 2005), pp. 3407-3412.
    by VY Gorbacheva, RV Kondratov, R Zhang, S Cherukuri, AV Gudkov, JS Takahashi, MP Antoch
    posted to bmal1 circadian_sensitivity clock cyclophosphamide knockout_mouse by uz_labu_laimi on 2007-09-13 21:53:15 as **
  • Protective effect of lipoic acid on cyclophosphamide-induced testicular toxicity.
    Clin Chim Acta, Vol. 367, No. 1-2. (May 2006), pp. 114-119.
    by E Selvakumar, C Prahalathan, PT Sudharsan, P Varalakshmi
    posted to cyclophosphamide gamma-glutamyl_transpeptidase lipoic_acid oxidative_stress testis by uz_labu_laimi on 2007-05-31 21:39:15 as ***
  • Role of glutathione in cellular resistance to alkylating agents
    Advances in Enzyme Regulation, Vol. 33 (1993), pp. 19-26.
    by Michael O Colvin, Henry S Friedman, Michael P Gamcsik, Catherine Fenselau, John Hilton
    posted to alkylating_agents alkylation cyclophosphamide glutathione review by uz_labu_laimi on 2007-03-22 17:49:14 as **
  • Application of computer-assisted sperm analysis system to elucidate lack of effects of cyclophosphamide on rat epididymal sperm motion.
    J Toxicol Sci, Vol. 26, No. 2. (May 2001), pp. 75-83.
    by H Higuchi, M Nakaoka, S Kawamura, Y Kamita, A Kohda, T Seki
    posted to casa cyclophosphamide motility rat spermatozoa by uz_labu_laimi on 2007-03-05 04:41:29 as **
  • Paternal exposure to cyclophosphamide dysregulates the gene activation program in rat preimplantation embryos.
    Mol Reprod Dev, Vol. 57, No. 3. (November 2000), pp. 214-223.
    by W Harrouk, S Khatabaksh, B Robaire, BF Hales
    posted to cyclophosphamide early_embryo embryo gene_expression male-mediated paternal_exposure preimplantation rat by uz_labu_laimi on 2007-03-27 18:49:37 as **
  • Effects of chronic low-dose cyclophosphamide exposure on the nuclei of rat spermatozoa.
    Biol Reprod, Vol. 52, No. 1. (January 1995), pp. 33-40.
    by J Qiu, BF Hales, B Robaire
    posted to cyclophosphamide dna_damage rat spermatozoa by uz_labu_laimi on 2007-03-27 19:10:41 as ***
  • Modified guanines representing O(6)-alkylation by the cyclophosphamide metabolites acrolein and chloroacetaldehyde: synthesis, stability, and ab initio studies.
    Chem Res Toxicol, Vol. 15, No. 3. (March 2002), pp. 380-387.
    by N Balu, MP Gamcsik, ME Colvin, OM Colvin, ME Dolan, SM Ludeman
    posted to acrolein alkylation chloroacetaldehyde cyclophosphamide guanine o6-alkylation by uz_labu_laimi on 2007-03-21 21:23:54 as **
  • Chemoprotective effect of lipoic acid against cyclophosphamide-induced changes in the rat sperm.
    Toxicology, Vol. 217, No. 1. (5 January 2006), pp. 71-78.
    by E Selvakumar, C Prahalathan, PT Sudharsan, P Varalakshmi
    posted to antioxidant cyclophosphamide dithiol lipoic_acid rat spermatozoa by uz_labu_laimi on 2007-05-28 19:58:32 as ***
  • Prophylactic action of melatonin against cyclophosphamide-induced oxidative stress in mice.
    Cell Biol Toxicol, Vol. 19, No. 6. (November 2003), pp. 367-372.
    by K Manda, AL Bhatia
    posted to cyclophosphamide glutathione melatonin mouse oxidative_stress by uz_labu_laimi on 2007-05-31 21:49:16 as *
  • Paternal exposure to cyclophosphamide induces DNA damage and alters the expression of DNA repair genes in the rat preimplantation embryo.
    Mutat Res, Vol. 461, No. 3. (9 November 2000), pp. 229-241.
    by W Harrouk, A Codrington, R Vinson, B Robaire, BF Hales
    posted to cyclophosphamide dna_damage dna_repair dna_repair_gene early_embryo embryo gene_expression male-mediated paternal_exposure preimplantation rat by uz_labu_laimi on 2007-03-27 18:48:47 as read
  • An overview of cyclophosphamide development and clinical applications.
    Curr Pharm Des, Vol. 5, No. 8. (August 1999), pp. 555-560.
    by OM Colvin
    posted to cyclophosphamide review by uz_labu_laimi on 2007-03-26 18:33:22 as **
  • Chronic cyclophosphamide treatment alters the expression of stress response genes in rat male germ cells.
    Biol Reprod, Vol. 66, No. 4. (April 2002), pp. 1024-1032.
    by A Aguilar-Mahecha, BF Hales, B Robaire
    posted to rat cyclophosphamide gene_expression male_germ_cell spermatogenesis stress_response_genes by uz_labu_laimi on 2007-03-20 20:35:40 as read
  • Testicular gametogenic and steroidogenic activities in cyclophosphamide treated rat: a correlative study with testicular oxidative stress.
    Drug Chem Toxicol, Vol. 25, No. 3. (August 2002), pp. 281-292.
    by D Ghosh, UB Das, S Ghosh, M Mallick, J Debnath
    posted to androgen cyclophosphamide gametogenesis oxidative_stress rat spermatogenesis steroidogenesis testis testosterone by uz_labu_laimi on 2007-05-28 05:56:03 as ***
  • Time for chronotherapy? Clock genes dictate sensitivity to cyclophosphamide.
    Proc Natl Acad Sci U S A, Vol. 102, No. 10. (8 March 2005), pp. 3529-3530.
    by CB Green
    posted to chronotherapy clock cyclophosphamide by uz_labu_laimi on 2007-09-13 21:51:48 as **
  • DNA damage in cyclophosphamide-resistant tumor cells: the role of glutathione.
    Cancer Res, Vol. 55, No. 8. (15 April 1995), pp. 1691-1695.
    by ME Richardson, DW Siemann
    posted to cyclophosphamide cyclophosphamide_resistance dna_damage glutathione tumour by uz_labu_laimi on 2007-03-22 17:52:31 as **
  • Evidence for a role of chloroethylaziridine in the cytotoxicity of cyclophosphamide.
    Cancer Chemother Pharmacol, Vol. 45, No. 4. (2000), pp. 335-344.
    by JL Flowers, SM Ludeman, MP Gamcsik, OM Colvin, KL Shao, JH Boal, JB Springer, DJ Adams
    posted to chloroethylaziridine cyclophosphamide cytotoxicity by uz_labu_laimi on 2007-03-21 21:34:07 as **
  • Treatment of radiation or cyclophosphamide induced hemorrhagic cystitis using conjugated estrogen.
    J Urol, Vol. 144, No. 1. (July 1990), pp. 41-43.
    by YK Liu, JI Harty, GS Steinbock, HA Holt, DH Goldstein, M Amin
    posted to conj-oestrogen cyclophosphamide cystitis man by szago on 2007-10-28 12:30:45 as **
  • Successful treatment of hemorrhagic cystitis secondary to cyclophosphamide chemotherapy with intravesical instillation of prostaglandin F2 alpha.
    Hinyokika Kiyo, Vol. 40, No. 9. (September 1994), pp. 833-835.
    by M Yamamoto, H Hibi, M Ohmura, K Miyake
    posted to cyclophosphamide cystitis man pgf by szago on 2007-10-28 12:29:25 as **
  • Prophylactic and therapeutic carboprost tromethamine bladder irrigation in rats with cyclophosphamide-induced hemorrhagic cystitis.
    J Urol, Vol. 148, No. 4. (October 1992), pp. 1326-1330.
    by DM Kranc, J Kim, F Straus, LA Levine
    posted to cyclophosphamide cystitis rat by szago on 2007-10-28 12:34:07 as **
  • De Novo Expression of Transfected Human Class 1 Aldehyde Dehydrogenase (ALDH) Causes Resistance to Oxazaphosphorine Anti-cancer Alkylating Agents in Hamster V79 Cell Lines
    J. Biol. Chem., Vol. 271, No. 20. (17 May 1996), pp. 11884-11890.
    by Kevin D Bunting, Alan J Townsend
    posted to aldh alternative cyclophosphamide metabolism p450 by jbolmarcich on 2008-01-09 23:23:47 as ***
  • Retinoic Acid Down-Regulates Aldehyde Dehydrogenase and Increases Cytotoxicity of 4-Hydroperoxycyclophosphamide and Acetaldehyde
    J Pharmacol Exp Ther, Vol. 312, No. 1. (1 January 2005), pp. 339-345.
    by Jan S Moreb, Amir Gabr, Govind R Vartikar, Santosh Gowda, James R Zucali, Dagmara Mohuczy
    posted to aldh cyclophosphamide metabolism by jbolmarcich on 2008-01-09 23:31:44 as read
  • DNA Damage Recognition in the Rat Zygote Following Chronic Paternal Cyclophosphamide Exposure
    Toxicol. Sci., Vol. 100, No. 2. (1 December 2007), pp. 495-503.
    by Tara S Barton, Bernard Robaire, Barbara F Hales
    posted to cyclophosphamide by jbolmarcich on 2008-01-10 00:04:49 as ***
  • Identification of cyclophosphamide-DNA adducts in rat embryos exposed in vitro to 4-hydroperoxycyclophosphamide.
    Chem Res Toxicol, Vol. 5, No. 3. (n 1992), pp. 382-385.
    by PE Mirkes, NA Brown, M Kajbaf, JH Lamb, PB Farmer, S Naylor
    posted to cyclophosphamide by ecattell on 2007-07-05 15:39:40 as **
  • Identification of phosphoramide mustard/DNA adducts using tandem mass spectrometry.
    Rapid Commun Mass Spectrom, Vol. 4, No. 10. (October 1990), pp. 410-414.
    by JR Cushnir, S Naylor, JH Lamb, PB Farmer, NA Brown, PE Mirkes
    posted to cyclophosphamide by ecattell on 2007-07-05 15:29:40 as **
  • A cyclophosphamide/DNA phosphoester adduct formed in vitro and in vivo.
    Cancer Res, Vol. 51, No. 3. (1 February 1991), pp. 886-892.
    by AE Maccubbin, L Caballes, JM Riordan, DH Huang, HL Gurtoo
    posted to cyclophosphamide by ecattell on 2007-07-05 15:41:35 as **
  • Reduced Intensity Conditioning (RIC) with Fludarabine, Busulfan and Cyclophosphamide for High Risk Patients with Thalassemia Major Undergoing Allogeneic Bone Marrow Transplantation Results in High Rejection Rates.
    ASH Annual Meeting Abstracts, Vol. 110, No. 11. (16 November 2007), 1998.
    by Mammen Chandy, Vikram Mathews, Biju George, Auro Vishwabandya, Salamun Desire, ML Kavitha, Alok Srivastava
    posted to allogeneic busulfan conditioning cyclophosphamide ferritin fludarabine high intensity reduced rejection ric risk thalassaemia thalassemia transplantation by akita on 2008-03-27 21:46:02 as read
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