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Ключевое слово egfr [150 articles]

Recent papers classified by the tag egfr.
  • Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis.
    J Biol Chem, Vol. 280, No. 37. (16 September 2005), pp. 32468-32479.
    by JX Zhu, S Goldoni, G Bix, RT Owens, DJ McQuillan, CC Reed, RV Iozzo
    posted to caveolae egfr endocytosis by zukeboy on 2005-10-27 17:54:47 as **
  • Activation of the Epidermal Growth Factor (EGF) Receptor Induces Formation of EGF Receptor- and Grb2-Containing Clathrin-Coated Pits
    Mol. Cell. Biol., Vol. 26, No. 2. (15 January 2006), pp. 389-401.
    by Lene E Johannessen, Nina M Pedersen, Ketil W Pedersen, Inger H Madshus, Espen Stang
    posted to clathrin egfr endocytosis by zukeboy on 2006-01-31 17:24:04 as ** along with 1 person pjasper
  • The Inhibitory Effect of ErbB2 on Epidermal Growth Factor-induced Formation of Clathrin-coated Pits Correlates with Retention of Epidermal Growth Factor Receptor-ErbB2 Oligomeric Complexes at the Plasma Membrane
    Mol. Biol. Cell, Vol. 16, No. 12. (1 December 2005), pp. 5832-5842.
    by Camilla Haslekas, Kamilla Breen, Ketil W Pedersen, Lene E Johannessen, Espen Stang, Inger H Madshus
    posted to clathrin egfr endocytosis by zukeboy on 2006-01-17 14:21:36 as ** along with 1 person pjasper
  • Inhibition of Growth Factor Production and Angiogenesis in Human Cancer Cells by ZD1839 (Iressa), a Selective Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor
    Clin Cancer Res, Vol. 7, No. 5. (1 May 2001), pp. 1459-1465.
    by Fortunato Ciardiello, Rosa Caputo, Roberto Bianco, Vincenzo Damiano, Gabriella Fontanini, Sabina Cuccato, Sabino De Placido, Raffaele A Bianco, Giampaolo Tortora
    posted to cancer cite egfr by zkyken on 2007-06-13 15:56:45 as **
  • Studies with CWR22 Xenografts in Nude Mice Suggest That ZD1839 May Have a Role in the Treatment of Both Androgen-dependent and Androgen-independent Human Prostate Cancer
    Clin Cancer Res, Vol. 8, No. 12. (1 December 2002), pp. 3870-3876.
    by Francis M Sirotnak, Yohung She, Fei Lee, Jing Chen, Howard I Scher
    posted to cite egfr fulltext hrpc therapy by zkyken on 2007-06-13 15:54:43 as **
  • Growth factors and their receptors: new targets for prostate cancer therapy.
    Urology, Vol. 58, No. 2 Suppl 1. (August 2001), pp. 114-122.
    by J Barton, G Blackledge, A Wakeling
    posted to cancer cite egfr prostate therapy by zkyken on 2007-06-13 15:52:20 as **
  • Changing pattern of expression of the epidermal growth factor receptor and transforming growth factor alpha in the progression of prostatic neoplasms
    Clin Cancer Res, Vol. 1, No. 5. (1 May 1995), pp. 545-550.
    by Hi Scher, A Sarkis, V Reuter, D Cohen, G Netto, D Petrylak, P Lianes, Z Fuks, J Mendelsohn, C Cordon-Cardo
    posted to cancer cite egfr fulltext prostate by zkyken on 2007-06-13 15:50:15 as **
  • A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor.
    Clin Cancer Res, Vol. 7, No. 10. (October 2001), pp. 2958-2970.
    by F Ciardiello, G Tortora
    posted to cite egfr fulltext by zkyken on 2007-06-13 15:45:07 as **
  • The epidermal growth factor receptor and its inhibition in cancer therapy.
    Pharmacol Ther, Vol. 82, No. 2-3. (n 1999), pp. 241-250.
    by JR Woodburn
    posted to cancer cite egfr by zkyken on 2007-06-13 15:42:53 as **
  • Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers.
    J Natl Cancer Inst, Vol. 97, No. 5. (2 March 2005), pp. 339-346.
    by H Shigematsu, L Lin, T Takahashi, M Nomura, M Suzuki, II Wistuba, KM Fong, H Lee, S Toyooka, N Shimizu, T Fujisawa, Z Feng, JA Roth, J Herz, JD Minna, AF Gazdar
    posted to egfr by zkyken on 2007-05-07 15:48:05 as **
  • Mutation in the tyrosine kinase domain of epidermal growth factor receptor is a predictive and prognostic factor for gefitinib treatment in patients with non-small cell lung cancer.
    Clin Cancer Res, Vol. 11, No. 10. (15 May 2005), pp. 3750-3757.
    by TY Chou, CH Chiu, LH Li, CY Hsiao, CY Tzen, KT Chang, YM Chen, RP Perng, SF Tsai, CM Tsai
    posted to egfr by zkyken on 2007-05-07 15:46:31 as **
  • Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in gefitinib-treated chemorefractory lung adenocarcinomas.
    Clin Cancer Res, Vol. 11, No. 16. (15 August 2005), pp. 5878-5885.
    by M Taron, Y Ichinose, R Rosell, T Mok, B Massuti, L Zamora, JL Mate, C Manegold, M Ono, C Queralt, T Jahan, JJ Sanchez, M Sanchez-Ronco, V Hsue, D Jablons, JM Sanchez, T Moran
    posted to cite egfr fulltext by zkyken on 2007-05-07 15:43:22 as **
  • Innovative therapies for prostate cancer treatment.
    Rev Urol, Vol. 5 Suppl 3 (2003)
    by S Syed, A Tolcher
    posted to egfr by zkyken on 2007-05-07 15:33:27 as **
  • Multigene reverse transcription-PCR profiling of circulating tumor cells in hormone-refractory prostate cancer.
    Clin Chem, Vol. 50, No. 5. (May 2004), pp. 826-835.
    by SM O'Hara, JG Moreno, DR Zweitzig, S Gross, LG Gomella, LW Terstappen
    posted to egfr by zkyken on 2007-05-07 15:30:46 as ****
  • Results from a pilot Phase I trial of gefitinib combined with docetaxel and estramustine in patients with hormone-refractory prostate cancer.
    Cancer, Vol. 106, No. 9. (1 May 2006), pp. 1917-1924.
    by G Wilding, P Soulie, D Trump, A Das-Gupta, E Small
    posted to egfr by zkyken on 2007-05-07 15:28:04 as ****
  • Absence of epidermal growth factor receptor gene mutations in patients with hormone refractory prostate cancer not responding to gefitinib.
    Prostate, Vol. 67, No. 6. (1 May 2007), pp. 603-604.
    by G Curigliano, G Pelosi, T De Pas, G Renne, O De Cobelli, M Manzotti, G Spitaleri, F de Braud
    posted to cite egfr hrpc by zkyken on 2007-05-07 15:22:38 as ***** along with 1 person and 1 group cursonivel1 cursonivel1
  • Identification of genes linked to gefitinib treatment in prostate cancer cell lines with or without resistance to androgen: a clue to application of gefitinib to hormone-resistant prostate cancer.
    Oncol Rep, Vol. 15, No. 6. (June 2006), pp. 1453-1460.
    by S Yano, H Matsuyama, H Hirata, R Inoue, H Matsumoto, C Ohmi, K Miura, M Shirai, N Iizuka, K Naito
    posted to cite egfr fulltext hrpc by zkyken on 2007-05-13 09:03:21 as **
  • Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression.
    Cancer research, Vol. 68, No. 6. (15 March 2008), pp. 1945-1952.
    by C Blázquez, M Salazar, A Carracedo, M Lorente, A Egia, L González-Feria, A Haro, G Velasco, M Guzmán
    posted to timp thc mmp egfr cannabinoid cancer by Yulquz on 2008-05-17 05:00:18 as **
  • Cannabinoids induce cancer cell proliferation via tumor necrosis factor alpha-converting enzyme (TACE/ADAM17)-mediated transactivation of the epidermal growth factor receptor.
    Cancer research, Vol. 64, No. 6. (15 March 2004), pp. 1943-1950.
    by S Hart, OM Fischer, A Ullrich
    posted to thc mmp egfr egf cancer by Yulquz on 2008-05-17 04:51:48 as **
  • Epidermal growth factor receptor amplification does not have prognostic significance in patients with glioblastoma multiforme.
    Int J Radiat Oncol Biol Phys, Vol. 63, No. 3. (1 November 2005), pp. 695-703.
    by AL Quan, GH Barnett, SY Lee, MA Vogelbaum, SA Toms, SM Staugaitis, RA Prayson, DM Peereboom, GH Stevens, BH Cohen, JH Suh
    posted to amplification egfr gbm marker prognostic by voldog on 2006-08-23 02:05:41 as **
  • Growth factors regulate heterogeneous nuclear ribonucleoprotein K expression and function.
    J Biol Chem, Vol. 276, No. 13. (30 March 2001), pp. 9699-9704.
    by M Mandal, R Vadlamudi, D Nguyen, RA Wang, L Costa, R Bagheri-Yarmand, J Mendelsohn, R Kumar
    posted to c-myc egf egfr growth_factor hnrnp_k by uz_labu_laimi on 2007-09-17 20:49:08 as ****
  • An Integrated Model of Epidermal Growth Factor Receptor Trafficking and Signal Transduction
    Biophys. J., Vol. 85, No. 2. (1 August 2003), pp. 730-743.
    by Haluk Resat, Jonathan A Ewald, David A Dixon, Steven H Wiley
    posted to egfr model signal_transduction stochastic by tuck on 2006-04-02 03:26:46 as **
  • Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.
    Mol Biol Cell, Vol. 12, No. 9. (September 2001), pp. 2629-2645.
    by L Qiao, E Studer, K Leach, R McKinstry, S Gupta, R Decker, R Kukreja, K Valerie, P Nagarkatti, W El Deiry, J Molkentin, R Schmidt-Ullrich, PB Fisher, S Grant, PB Hylemon, P Dent
    posted to apoptosis detergent doc egfr fas by tsjipko on 2006-10-02 12:40:41 as **
  • Ligand-independent activation of the EGFR by lipid raft disruption.
    J Invest Dermatol, Vol. 126, No. 5. (May 2006), pp. 954-962.
    by S Lambert, D Vind-Kezunovic, S Karvinen, R Gniadecki
    posted to cholesterol depletion egfr ligand-independent rafts by tsjipko on 2006-10-02 12:35:16 as ** along with 1 person pjasper
  • Notch, epidermal growth factor receptor, and beta1-integrin pathways are coordinated in neural stem cells.
    J Biol Chem, Vol. 281, No. 8. (24 February 2006), pp. 5300-5309.
    by LS Campos, L Decker, V Taylor, W Skarnes
    posted to caveolin-1 egfr integrin notch stem_cell by tsjipko on 2006-10-09 09:49:24 as **
  • EGFR Intron Recombination in Human Gliomas: Inappropriate Diversion of V(D)J Recombination?
    Current genomics, Vol. 8, No. 3. (May 2007), pp. 163-170.
    by RA Fenstermaker, MJ Ciesielski
    posted to vdjrecombination nhej egfr by TOchi on 2008-08-03 10:22:30 as **
  • PKCdelta and Calmodulin Regulate EGF Receptor Recycling from Early Endosomes through Arp2/3 Complex and Cortactin.
    Mol Biol Cell (24 October 2007)
    by Anna Lladó, Paul Timpson, Sandra Vilà de Muga, Jemina Moretó, Albert Pol, Thomas Grewal, Roger J J Daly, Carlos Enrich, Francesc Tebar
    posted to egfr recycling by tkershaw on 2007-10-29 09:10:53 as **
  • notes Modeling and computational analysis of EGF receptor-mediated cell communication in Drosophila oogenesis.
    Development, Vol. 129, No. 11. (June 2002), pp. 2577-2589.
    by SY Shvartsman, CB Muratov, DA Lauffenburger
    posted to computational development drosophila egfr modelling by rklancer on 2004-11-10 05:53:43
  • Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo.
    Cancer Res, Vol. 61, No. 24. (15 December 2001), pp. 8887-8895.
    by SL Moulder, FM Yakes, SK Muthuswamy, R Bianco, JF Simpson, CL Arteaga
    posted to egfr erbb2 inactive_dimer iressa by pjasper on 2007-05-10 20:38:57 as *****
  • ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells.
    Clin Cancer Res, Vol. 9, No. 4. (April 2003), pp. 1274-1283.
    by J Anido, P Matar, J Albanell, M Guzmán, F Rojo, J Arribas, S Averbuch, J Baselga
    posted to egfr erbb2 erbb3 inactive_dimer iressa by pjasper on 2007-05-10 20:36:31 as ***** along with 1 person brianb
  • Unliganded epidermal growth factor receptor dimerization induced by direct interaction of quinazolines with the ATP binding site.
    J Biol Chem, Vol. 272, No. 37. (12 September 1997), pp. 23247-23254.
    by CL Arteaga, TT Ramsey, LK Shawver, CA Guyer
    posted to egfr erbb2 inactive_dimer inhibitor by pjasper on 2007-05-10 20:34:56 as *****
  • Signaling-inactive epidermal growth factor receptor/ligand complexes in intact carcinoma cells by quinazoline tyrosine kinase inhibitors.
    Cancer Res, Vol. 61, No. 15. (1 August 2001), pp. 5790-5795.
    by RB Lichtner, A Menrad, A Sommer, U Klar, MR Schneider
    posted to egfr inhibitor by pjasper on 2007-05-10 20:30:15 as *****
  • Intersectin regulates epidermal growth factor receptor endocytosis, ubiquitylation, and signaling.
    Mol Pharmacol, Vol. 70, No. 5. (November 2006), pp. 1643-1653.
    by NP Martin, RP Mohney, S Dunn, M Das, E Scappini, JP O'Bryan
    posted to degradation egfr internalization intersectin by pjasper on 2007-04-26 17:06:18 as **
  • Epidermal growth factor receptor fate is controlled by Hrs tyrosine phosphorylation sites that regulate Hrs degradation.
    Mol Cell Biol, Vol. 27, No. 3. (February 2007), pp. 888-898.
    by KA Stern, GD Visser Smit, TL Place, S Winistorfer, RC Piper, NL Lill
    posted to degradation egfr internalization by pjasper on 2007-04-25 20:14:35 as **
  • EGF receptor activation: push comes to shove.
    Cell, Vol. 125, No. 6. (16 June 2006), pp. 1029-1031.
    by SR Hubbard
    posted to activation comment egfr structure by pjasper on 2007-04-25 20:57:44 as **
  • HER2 overexpression increases sensitivity to gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, through inhibition of HER2/HER3 heterodimer formation in lung cancer cells.
    Cancer Res, Vol. 65, No. 10. (15 May 2005), pp. 4253-4260.
    by A Hirata, F Hosoi, M Miyagawa, S Ueda, S Naito, T Fujii, M Kuwano, M Ono
    posted to egfr erbb2 inhibitor iressa nsclc by pjasper on 2007-05-10 19:52:18 as ***** along with 1 person js229
  • An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor.
    Cell, Vol. 125, No. 6. (16 June 2006), pp. 1137-1149.
    by X Zhang, J Gureasko, K Shen, PA Cole, J Kuriyan
    posted to activation egfr by pjasper on 2007-04-25 20:56:57 as **
  • Epidermal Growth Factor Receptor Activation in Glioblastoma through Novel Missense Mutations in the Extracellular Domain.
    PLoS Med, Vol. 3, No. 12. (19 December 2006)
    by Jeffrey C C Lee, Igor Vivanco, Rameen Beroukhim, Julie H Y H Huang, Whei L L Feng, Ralph M M Debiasi, Koji Yoshimoto, Jennifer C C King, Phioanh Nghiemphu, Yuki Yuza, Qing Xu, Heidi Greulich, Roman K K Thomas, J Guillermo G Paez, Timothy C C Peck, David J J Linhart, Karen A A Glatt, Gad Getz, Robert Onofrio, Liuda Ziaugra, Ross L L Levine, Stacey Gabriel, Tomohiro Kawaguchi, Keith O'neill, Haumith Khan, Linda M M Liau, Stanley F F Nelson, P Nagesh N Rao, Paul Mischel, Russell O O Pieper, Tim Cloughesy, Daniel J J Leahy, William R R Sellers, Charles L L Sawyers, Matthew Meyerson, Ingo K K Mellinghoff
    posted to egfr glioblastoma mutation by pjasper on 2007-04-26 17:30:11 as **
  • Targeted antireceptor therapy with monoclonal antibodies leads to the formation of inactivated tetrameric forms of ErbB receptors.
    J Immunol, Vol. 178, No. 2. (15 January 2007), pp. 1021-1029.
    by K Furuuchi, A Berezov, T Kumagai, MI Greene
    posted to egfr inhibitor tetramer by pjasper on 2007-05-08 18:06:47 as **
  • p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration
    The EMBO Journal, Vol. aop, No. current. (30 November 2006)
    by Mark R Frey, Rebecca S Dise, Karen L Edelblum, Brent D Polk
    posted to egfr internalization migration p38 by pjasper on 2007-04-26 17:28:34 as **
  • Antitumor activity of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib (ZD1839, Iressa) in non-small cell lung cancer cell lines correlates with gene copy number and EGFR mutations but not EGFR protein levels.
    Clin Cancer Res, Vol. 12, No. 23. (1 December 2006), pp. 7117-7125.
    by BA Helfrich, D Raben, M Varella-Garcia, D Gustafson, DC Chan, L Bemis, C Coldren, A Barón, C Zeng, WA Franklin, FR Hirsch, A Gazdar, J Minna, PA Bunn
    posted to akt egfr genomics iressa mutation nsclc by pjasper on 2007-04-26 17:27:15 as **
  • Unligated Epidermal Growth Factor Receptor Forms Higher Order Oligomers within Microclusters on A431 Cells That Are Sensitive to Tyrosine Kinase Inhibitor Binding.
    Biochemistry, Vol. 46, No. 15. (17 April 2007), pp. 4589-4597.
    by AH Clayton, ML Tavarnesi, TG Johns
    posted to a431 egfr oligomer structure by pjasper on 2007-05-08 19:12:05 as **
  • The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis.
    Exp Cell Res, Vol. 313, No. 8. (1 May 2007), pp. 1696-1709.
    by V Bertelsen, K Breen, K Sandvig, E Stang, IH Madshus
    posted to cbl egfr internalization tula by pjasper on 2007-05-08 19:11:19 as **
  • Epidermal growth factor receptor targeting in cancer.
    Semin Oncol, Vol. 33, No. 4. (August 2006), pp. 369-385.
    by J Mendelsohn, J Baselga
    posted to egfr inhibitor review by pjasper on 2007-04-25 22:10:25 as **
  • Cool-1 functions as an essential regulatory node for EGFreceptor- and Src-mediated cell growth
    Nature Cell Biology, Vol. 8, No. 9. (06 August 2006), pp. 945-956.
    by Qiyu Feng, Dan Baird, Xu Peng, Jianbin Wang, Thi Ly, Jun-Lin Guan, Richard A Cerione
    posted to cool1 egfr src by pjasper on 2007-04-25 22:08:37 as **
  • Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival.
    Br J Cancer, Vol. 96 Suppl (2007)
    by HW Lo, MC Hung
    posted to egfr nucleus by pjasper on 2007-05-08 19:08:25 as **
  • Gefitinib (IRESSA) sensitive lung cancer cell lines show phosphorylation of Akt without ligand stimulation
    BMC Cancer, Vol. 6 (06 December 2006), 277.
    by Rintaro Noro, Akihiko Gemma, Seiji Kosaihira, Yutaka Kokubo, Mingwei Chen, Masahiro Seike, Kiyoko Kataoka, Kuniko Matsuda, Tetsuya Okano, Yuji Minegishi, Akinobu Yoshimura, Shoji Kudoh
    posted to activation akt egfr mutation by pjasper on 2007-04-26 17:24:36 as ** along with 1 person Kyaita
  • Mutational activation of ErbB family receptor tyrosine kinases: insights into mechanisms of signal transduction and tumorigenesis.
    Bioessays, Vol. 29, No. 6. (16 May 2007), pp. 558-565.
    by David J J Riese, Richard M M Gallo, Jeffrey Settleman
    posted to egfr mutant review by pjasper on 2007-05-22 20:38:16 as **
  • Activation of the EGFR gene target EphA2 inhibits epidermal growth factor-induced cancer cell motility.
    Mol Cancer Res, Vol. 5, No. 3. (March 2007), pp. 283-293.
    by AB Larsen, MW Pedersen, MT Stockhausen, MV Grandal, B van Deurs, HS Poulsen
    posted to egfr epha2 by pjasper on 2007-05-08 19:04:25 as **
  • Cross Talk between c-Met and Epidermal Growth Factor Receptor during Retinal Pigment Epithelial Wound Healing.
    Invest Ophthalmol Vis Sci, Vol. 48, No. 5. (May 2007), pp. 2242-2248.
    by KP Xu, FS Yu
    posted to egfr met by pjasper on 2007-05-08 20:55:53 as **
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