Detecting the undetectable: uncovering duplicated segments in Arabidopsis by comparison with rice

by: Klaas Vandepoele, Cedric Simillion, Yves Van de Peer

Trends in Genetics, Vol. 18, No. 12. (1 December 2002), pp. 606-608.

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analyses, duplication, homology

Abstract

Genome analysis shows that large-scale gene duplications have occurred in fungi, animals and plants, creating genomic regions that show similarity in gene content and order. However, the high frequency of gene loss reduces colinearity resulting in duplicated regions that, in the extreme, no longer share homologous genes. Here, we show that by comparison with an appropriate second genome, such paralogous regions can still be identified.

@article{Vandepoele2002, abstract = {Genome analysis shows that large-scale gene duplications have occurred in fungi, animals and plants, creating genomic regions that show similarity in gene content and order. However, the high frequency of gene loss reduces colinearity resulting in duplicated regions that, in the extreme, no longer share homologous genes. Here, we show that by comparison with an appropriate second genome, such paralogous regions can still be identified.}, author = {Vandepoele, Klaas and Simillion, Cedric and Van de Peer, Yves }, citeulike-article-id = {2845170}, doi = {http://dx.doi.org/10.1016/S0168-9525(02)02796-8}, journal = {Trends in Genetics}, keywords = {analyses, duplication, homology}, month = {December}, number = {12}, pages = {606--608}, posted-at = {2008-05-29 17:45:07}, priority = {2}, title = {Detecting the undetectable: uncovering duplicated segments in Arabidopsis by comparison with rice}, url = {http://dx.doi.org/10.1016/S0168-9525(02)02796-8}, volume = {18}, year = {2002} }

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TY - JOUR ID - Vandepoele2002 L3 - citeulike-article-id:2845170 TI - Detecting the undetectable: uncovering duplicated segments in Arabidopsis by comparison with rice JF - Trends in Genetics VL - 18 IS - 12 SP - 606 EP - 608 N2 - Genome analysis shows that large-scale gene duplications have occurred in fungi, animals and plants, creating genomic regions that show similarity in gene content and order. However, the high frequency of gene loss reduces colinearity resulting in duplicated regions that, in the extreme, no longer share homologous genes. Here, we show that by comparison with an appropriate second genome, such paralogous regions can still be identified. KW - analyses KW - duplication KW - homology AU - Vandepoele, Klaas AU - Simillion, Cedric AU - Van de Peer, Yves PY - 2002/12/01/ UR - http://dx.doi.org/10.1016/S0168-9525(02)02796-8 ER -

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