Ensemble patterns of hippocampal CA3-CA1 neurons during sharp wave-associated population events.

@article{citeulike:2210870, abstract = {Transfer of neuronal patterns from the CA3 to CA1 region was studied by simultaneous recording of neuronal ensembles in the behaving rat. A nonlinear interaction among pyramidal neurons was observed during sharp wave (SPW)-related population bursts, with stronger synchrony associated with more widespread spatial coherence. SPW bursts emerged in the CA3a-b subregions and spread to CA3c before invading the CA1 area. Synchronous discharge of >10\% of the CA3 within a 100 ms window was required to exert a detectable influence on CA1 pyramidal cells. Activity of some CA3 pyramidal neurons differentially predicted the ripple-related discharge of circumscribed groups of CA1 pyramidal cells. We suggest that, in SPW behavioral state, the coherent discharge of a small group of CA3 cells is the primary cause of spiking activity in CA1 pyramidal neurons.}, address = {Center for Molecular and Behavioral Neuroscience, Rutgers University, The State University of New Jersey, Newark 07102, USA.}, author = {Csicsvari, J. and Hirase, H. and Mamiya, A. and Buzs\'{a}ki, G. }, citeulike-article-id = {2210870}, issn = {0896-6273}, journal = {Neuron}, keywords = {reactivation, spw}, month = {November}, number = {2}, pages = {585--594}, posted-at = {2008-01-09 13:05:27}, priority = {2}, title = {Ensemble patterns of hippocampal CA3-CA1 neurons during sharp wave-associated population events.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/11144366}, volume = {28}, year = {2000} }

TY - JOUR ID - citeulike:2210870 L3 - citeulike-article-id:2210870 TI - Ensemble patterns of hippocampal CA3-CA1 neurons during sharp wave-associated population events. JF - Neuron VL - 28 IS - 2 SP - 585 EP - 594 AD - Center for Molecular and Behavioral Neuroscience, Rutgers University, The State University of New Jersey, Newark 07102, USA. SN - 0896-6273 N2 - Transfer of neuronal patterns from the CA3 to CA1 region was studied by simultaneous recording of neuronal ensembles in the behaving rat. A nonlinear interaction among pyramidal neurons was observed during sharp wave (SPW)-related population bursts, with stronger synchrony associated with more widespread spatial coherence. SPW bursts emerged in the CA3a-b subregions and spread to CA3c before invading the CA1 area. Synchronous discharge of >10% of the CA3 within a 100 ms window was required to exert a detectable influence on CA1 pyramidal cells. Activity of some CA3 pyramidal neurons differentially predicted the ripple-related discharge of circumscribed groups of CA1 pyramidal cells. We suggest that, in SPW behavioral state, the coherent discharge of a small group of CA3 cells is the primary cause of spiking activity in CA1 pyramidal neurons. KW - reactivation KW - spw AU - Csicsvari, J AU - Hirase, H AU - Mamiya, A AU - Buzsáki, G PY - 2000/11// UR - http://view.ncbi.nlm.nih.gov/pubmed/11144366 ER -