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DNA Tile Based Self-Assembly: Building Complex Nanoarchitectures

by: Chenxiang Lin, Yan Liu, Sherri Rinker, Hao Yan
ChemPhysChem, Vol. 7, No. 8. (2006), pp. 1641-1647.


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DNA tile based self-assembly provides an attractive route to create nanoarchitectures of programmable patterns. It also offers excellent scaffolds for directed self-assembly of nanometer-scale materials, ranging from nanoparticles to proteins, with potential applications in constructing nanoelectronic/nanophotonic devices and protein/ligand nanoarrays. This Review first summarizes the currently available DNA tile toolboxes and further emphasizes recent developments toward self-assembling DNA nanostructures with increasing complexity. Exciting progress using DNA tiles for directed self-assembly of other nanometer scale components is also discussed.


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