One-component systems dominate signal transduction in prokaryotes.

by: LE Ulrich, EV Koonin, IB Zhulin

Trends Microbiol, Vol. 13, No. 2. (February 2005), pp. 52-56.

View FullText article

DOI, Pubmed, Hubmed

Reviews [Write a review of this article]

There are no reviews of this article

Find related articles from these CiteULike users

matzke, chrn, beatrizfernandez, Microbial-Ecology (group)

Find related articles with these CiteULike tags

chemotaxis, flag, ic, pathway, refs_ox, signal, transduction

Abstract

Two-component systems that link environmental signals to cellular responses are viewed as the primary mode of signal transduction in prokaryotes. By analyzing information encoded by 145 prokaryotic genomes, we found that the majority of signal transduction systems consist of a single protein that contains input and output domains but lacks phosphotransfer domains typical of two-component systems. One-component systems are evolutionarily older, more widely distributed among bacteria and archaea, and display a greater diversity of domains than two-component systems.

@article{citeulike:422045, abstract = {Two-component systems that link environmental signals to cellular responses are viewed as the primary mode of signal transduction in prokaryotes. By analyzing information encoded by 145 prokaryotic genomes, we found that the majority of signal transduction systems consist of a single protein that contains input and output domains but lacks phosphotransfer domains typical of two-component systems. One-component systems are evolutionarily older, more widely distributed among bacteria and archaea, and display a greater diversity of domains than two-component systems.}, address = {Center for Bioinformatics and Computational Biology, School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA.}, author = {Ulrich, L. E. and Koonin, E. V. and Zhulin, I. B. }, citeulike-article-id = {422045}, doi = {http://dx.doi.org/10.1016/j.tim.2004.12.006}, issn = {0966-842X}, journal = {Trends Microbiol}, keywords = {transduction}, month = {February}, number = {2}, pages = {52--56}, posted-at = {2007-09-19 11:55:46}, priority = {2}, title = {One-component systems dominate signal transduction in prokaryotes.}, url = {http://dx.doi.org/10.1016/j.tim.2004.12.006}, volume = {13}, year = {2005} }

RIS record

TY - JOUR ID - citeulike:422045 L3 - citeulike-article-id:422045 TI - One-component systems dominate signal transduction in prokaryotes. JF - Trends Microbiol VL - 13 IS - 2 SP - 52 EP - 56 AD - Center for Bioinformatics and Computational Biology, School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA. SN - 0966-842X N2 - Two-component systems that link environmental signals to cellular responses are viewed as the primary mode of signal transduction in prokaryotes. By analyzing information encoded by 145 prokaryotic genomes, we found that the majority of signal transduction systems consist of a single protein that contains input and output domains but lacks phosphotransfer domains typical of two-component systems. One-component systems are evolutionarily older, more widely distributed among bacteria and archaea, and display a greater diversity of domains than two-component systems. KW - transduction AU - Ulrich, LE AU - Koonin, EV AU - Zhulin, IB PY - 2005/02// UR - http://dx.doi.org/10.1016/j.tim.2004.12.006 ER -

RIS BibTeX