Direct Intracranial, fMRI, and Lesion Evidence for the Causal Role of Left Inferotemporal Cortex in Reading

@article{citeulike:2318040, abstract = {Summary Models of the "visual word form system" postulate that a left occipitotemporal region implements the automatic visual word recognition required for efficient reading. This theory was assessed in a patient in whom reading was explored with behavioral measures, fMRI, and intracranial local field potentials. Prior to surgery, when reading was normal, fMRI revealed a normal mosaic of ventral visual selectivity for words, faces, houses, and tools. Intracranial recordings demonstrated that the left occipitotemporal cortex responded with a short latency to conscious but also to subliminal words. Surgery removed a small portion of word-responsive occipitotemporal cortex overlapping with the word-specific fMRI activation. The patient developed a marked reading deficit, while recognition of other visual categories remained intact. Furthermore, in the post-surgery fMRI map of visual cortex, only word-specific activations disappeared. Altogether, these results provide direct evidence for the causal role of the left occipitotemporal cortex in the recognition of visual words.}, author = {Gaillard, Raphael and Naccache, Lionel and Pinel, Philippe and Clemenceau, Stephane and Volle, Emmanuelle and Hasboun, Dominique and Dupont, Sophie and Baulac, Michel and Dehaene, Stanislas and Adam, Claude and Cohen, Laurent }, citeulike-article-id = {2318040}, doi = {10.1016/j.neuron.2006.03.031}, journal = {Neuron}, keywords = {cogneuro-spring2008}, month = {April}, number = {2}, pages = {191--204}, posted-at = {2008-02-09 00:20:39}, priority = {3}, title = {Direct Intracranial, fMRI, and Lesion Evidence for the Causal Role of Left Inferotemporal Cortex in Reading}, url = {http://dx.doi.org/10.1016/j.neuron.2006.03.031}, volume = {50}, year = {2006} }

TY - JOUR ID - citeulike:2318040 L3 - citeulike-article-id:2318040 TI - Direct Intracranial, fMRI, and Lesion Evidence for the Causal Role of Left Inferotemporal Cortex in Reading JF - Neuron VL - 50 IS - 2 SP - 191 EP - 204 N2 - Summary Models of the "visual word form system" postulate that a left occipitotemporal region implements the automatic visual word recognition required for efficient reading. This theory was assessed in a patient in whom reading was explored with behavioral measures, fMRI, and intracranial local field potentials. Prior to surgery, when reading was normal, fMRI revealed a normal mosaic of ventral visual selectivity for words, faces, houses, and tools. Intracranial recordings demonstrated that the left occipitotemporal cortex responded with a short latency to conscious but also to subliminal words. Surgery removed a small portion of word-responsive occipitotemporal cortex overlapping with the word-specific fMRI activation. The patient developed a marked reading deficit, while recognition of other visual categories remained intact. Furthermore, in the post-surgery fMRI map of visual cortex, only word-specific activations disappeared. Altogether, these results provide direct evidence for the causal role of the left occipitotemporal cortex in the recognition of visual words. KW - cogneuro-spring2008 AU - Gaillard, Raphael AU - Naccache, Lionel AU - Pinel, Philippe AU - Clemenceau, Stephane AU - Volle, Emmanuelle AU - Hasboun, Dominique AU - Dupont, Sophie AU - Baulac, Michel AU - Dehaene, Stanislas AU - Adam, Claude AU - Cohen, Laurent PY - 2006/04/20/ UR - http://dx.doi.org/10.1016/j.neuron.2006.03.031 ER -