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1995 1996 2008 264 action activation adrenoreceptor agonist alpha atlantic beta binding bond bovine bursicon cam cedim cg chimera chromophore complex conservation cross cryptic d264 d264e dimerization dry dynamics ecd endocr endocrine endocrinology evolution exoloop fep fish fly fsh fshr genes glycoprotein-hormone gpa2 gpb5 gpcr gphr gproteins hcg helix hinge histamine hormone hydrogen hydrophobic infertility interaction jbc krause lh lhr lmw lowmolecularweigth lrr mechanism membran membrane mine mm_pbsa model mol monomer moyle mutation nature ohss oligosaccharides palczewski pardo patients poket protein r136 receptor resolution review rhodopsin rhodpsin s339a sequence ser281 signal signaling site sohss structure sulfated thyrostimulin tm7 tmd transmembrane transmenbrane tsh tshr tshr_rat tyrosine tyyrostimulin upper-ionic-lock wrong x-ray

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