Searching for a baseline: functional imaging and the resting human brain.

by: DA Gusnard, ME Raichle, ME Raichle

Nat Rev Neurosci, Vol. 2, No. 10. (October 2001), pp. 685-694.

View FullText article

DOI, Nature, Pubmed, Hubmed

Reviews [Write a review of this article]

There are no reviews of this article

Find related articles from these CiteULike users

pbellec, pervane, xinian, ITra, josepe, suizan, Functional_Imaging (group), resting-state_networks (group)

Find related articles with these CiteULike tags

baseline, bold, cortex, deactivation, default, default-mode, fmri, functional, imaging, mode, pet, resting-state, review, rsn, spontaneous_activity

Abstract

Functional brain imaging in humans has revealed task-specific increases in brain activity that are associated with various mental activities. In the same studies, mysterious, task-independent decreases have also frequently been encountered, especially when the tasks of interest have been compared with a passive state, such as simple fixation or eyes closed. These decreases have raised the possibility that there might be a baseline or resting state of brain function involving a specific set of mental operations. We explore this possibility, including the manner in which we might define a baseline and the implications of such a baseline for our understanding of brain function.

@article{citeulike:790119, abstract = {Functional brain imaging in humans has revealed task-specific increases in brain activity that are associated with various mental activities. In the same studies, mysterious, task-independent decreases have also frequently been encountered, especially when the tasks of interest have been compared with a passive state, such as simple fixation or eyes closed. These decreases have raised the possibility that there might be a baseline or resting state of brain function involving a specific set of mental operations. We explore this possibility, including the manner in which we might define a baseline and the implications of such a baseline for our understanding of brain function.}, address = {The Mallinckrodt Institute of Radiology, Washington University, St Louis, Missouri 63110, USA.}, author = {Gusnard, D. A. and Raichle, M. E. and Raichle, M. E. }, citeulike-article-id = {790119}, doi = {10.1038/35094500}, issn = {1471-003X}, journal = {Nat Rev Neurosci}, keywords = {bold, cortex, fmri, functional, imaging, spontaneous\_activity}, month = {October}, number = {10}, pages = {685--694}, posted-at = {2007-11-10 06:08:54}, priority = {2}, title = {Searching for a baseline: functional imaging and the resting human brain.}, url = {http://dx.doi.org/10.1038/35094500}, volume = {2}, year = {2001} }

RIS record

TY - JOUR ID - citeulike:790119 L3 - citeulike-article-id:790119 TI - Searching for a baseline: functional imaging and the resting human brain. JF - Nat Rev Neurosci VL - 2 IS - 10 SP - 685 EP - 694 AD - The Mallinckrodt Institute of Radiology, Washington University, St Louis, Missouri 63110, USA. SN - 1471-003X N2 - Functional brain imaging in humans has revealed task-specific increases in brain activity that are associated with various mental activities. In the same studies, mysterious, task-independent decreases have also frequently been encountered, especially when the tasks of interest have been compared with a passive state, such as simple fixation or eyes closed. These decreases have raised the possibility that there might be a baseline or resting state of brain function involving a specific set of mental operations. We explore this possibility, including the manner in which we might define a baseline and the implications of such a baseline for our understanding of brain function. KW - bold KW - cortex KW - fmri KW - functional KW - imaging KW - spontaneous_activity AU - Gusnard, DA AU - Raichle, ME AU - Raichle, ME PY - 2001/10// UR - http://dx.doi.org/10.1038/35094500 ER -

RIS BibTeX