GeneSeeker: extraction and integration of human disease-related information from web-based genetic databases.

@article{citeulike:1932453, abstract = {The identification of genes underlying human genetic disorders requires the combination of data related to cytogenetic localization, phenotypes and expression patterns, to generate a list of candidate genes. In the field of human genetics, it is normal to perform this combination analysis by hand. We report on GeneSeeker (http://www.cmbi.ru.nl/GeneSeeker/), a web server that gathers and combines data from a series of databases. All database searches are performed via the web interfaces provided with the original databases, guaranteeing that the most recent data are queried, and obviating data warehousing. GeneSeeker makes the same selection of candidate genes as the human geneticists would have performed, and thus reducing the time-consuming process to a few minutes. GeneSeeker is particularly well suited for syndromes in which the disease gene displays altered expression patterns in the affected tissue(s).}, address = {Centre for Molecular and Biomolecular Informatics, Radboud University Nijmegen, PO Box 9010, 6500GL Nijmegen, The Netherlands.}, author = {van Driel, M. A. and Cuelenaere, K. and Kemmeren, P. P. and Leunissen, J. A. and Brunner, H. G. and Vriend, G. }, citeulike-article-id = {1932453}, issn = {1362-4962}, journal = {Nucleic Acids Res}, month = {July}, number = {Web Server issue}, posted-at = {2007-11-18 08:08:00}, priority = {2}, title = {GeneSeeker: extraction and integration of human disease-related information from web-based genetic databases.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/15980578}, volume = {33}, year = {2005} }

TY - JOUR ID - citeulike:1932453 L3 - citeulike-article-id:1932453 TI - GeneSeeker: extraction and integration of human disease-related information from web-based genetic databases. JF - Nucleic Acids Res VL - 33 IS - Web Server issue AD - Centre for Molecular and Biomolecular Informatics, Radboud University Nijmegen, PO Box 9010, 6500GL Nijmegen, The Netherlands. SN - 1362-4962 N2 - The identification of genes underlying human genetic disorders requires the combination of data related to cytogenetic localization, phenotypes and expression patterns, to generate a list of candidate genes. In the field of human genetics, it is normal to perform this combination analysis by hand. We report on GeneSeeker (http://www.cmbi.ru.nl/GeneSeeker/), a web server that gathers and combines data from a series of databases. All database searches are performed via the web interfaces provided with the original databases, guaranteeing that the most recent data are queried, and obviating data warehousing. GeneSeeker makes the same selection of candidate genes as the human geneticists would have performed, and thus reducing the time-consuming process to a few minutes. GeneSeeker is particularly well suited for syndromes in which the disease gene displays altered expression patterns in the affected tissue(s). AU - van Driel, MA AU - Cuelenaere, K AU - Kemmeren, PP AU - Leunissen, JA AU - Brunner, HG AU - Vriend, G PY - 2005/07/01/ UR - http://view.ncbi.nlm.nih.gov/pubmed/15980578 ER -