Informatics and computational strategies for the study of lipids.

by: L Yetukuri, K Ekroos, A Vidal-Puig, M Oresic

Molecular bioSystems, Vol. 4, No. 2. (February 2008), pp. 121-127.

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Abstract

Recent advances in mass spectrometry (MS)-based techniques for lipidomic analysis have empowered us with the tools that afford studies of lipidomes at the systems level. However, these techniques pose a number of challenges for lipidomic raw data processing, lipid informatics, and the interpretation of lipidomic data in the context of lipid function and structure. Integration of lipidomic data with other systemic levels, such as genomic or proteomic, in the context of molecular pathways and biophysical processes provides a basis for the understanding of lipid function at the systems level. The present report, based on the limited literature, is an update on a young but rapidly emerging field of lipid informatics and related pathway reconstruction strategies.

@article{citeulike:2801110, abstract = {Recent advances in mass spectrometry (MS)-based techniques for lipidomic analysis have empowered us with the tools that afford studies of lipidomes at the systems level. However, these techniques pose a number of challenges for lipidomic raw data processing, lipid informatics, and the interpretation of lipidomic data in the context of lipid function and structure. Integration of lipidomic data with other systemic levels, such as genomic or proteomic, in the context of molecular pathways and biophysical processes provides a basis for the understanding of lipid function at the systems level. The present report, based on the limited literature, is an update on a young but rapidly emerging field of lipid informatics and related pathway reconstruction strategies.}, address = {VTT Technical Research Centre of Finland, Tietotie 2, FI-02044 VTT, Espoo, Finland.}, author = {Yetukuri, L. and Ekroos, K. and Vidal-Puig, A. and Oresic, M. }, citeulike-article-id = {2801110}, doi = {10.1039/b715468b}, issn = {1742-206X}, journal = {Molecular bioSystems}, month = {February}, number = {2}, pages = {121--127}, posted-at = {2008-05-15 10:27:29}, priority = {2}, title = {Informatics and computational strategies for the study of lipids.}, url = {http://dx.doi.org/10.1039/b715468b}, volume = {4}, year = {2008} }

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TY - JOUR ID - citeulike:2801110 L3 - citeulike-article-id:2801110 TI - Informatics and computational strategies for the study of lipids. JF - Molecular bioSystems VL - 4 IS - 2 SP - 121 EP - 127 AD - VTT Technical Research Centre of Finland, Tietotie 2, FI-02044 VTT, Espoo, Finland. SN - 1742-206X N2 - Recent advances in mass spectrometry (MS)-based techniques for lipidomic analysis have empowered us with the tools that afford studies of lipidomes at the systems level. However, these techniques pose a number of challenges for lipidomic raw data processing, lipid informatics, and the interpretation of lipidomic data in the context of lipid function and structure. Integration of lipidomic data with other systemic levels, such as genomic or proteomic, in the context of molecular pathways and biophysical processes provides a basis for the understanding of lipid function at the systems level. The present report, based on the limited literature, is an update on a young but rapidly emerging field of lipid informatics and related pathway reconstruction strategies. AU - Yetukuri, L AU - Ekroos, K AU - Vidal-Puig, A AU - Oresic, M PY - 2008/02// UR - http://dx.doi.org/10.1039/b715468b ER -

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