Layer specific somatosensory cortical activation during active tactile discrimination

by: DJ Krupa, MC Wiest, MG Shuler, M Laubach, MAL Nicolelis

Science, Vol. 304 (2004), pp. 1989-1992.

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Abstract

Ensemble neuronal activity was recorded in each layer of the whisker area of primary somatosensory cortex (SI) while rats performed a whisker-dependent tactile discrimination. Comparison with SI activity evoked by similar passive whisker stimulation revealed fundamental differences in tactile signal processing during active and passive stimulation. Moreover, significant layer-specific functional differences in SI activity were observed during active discrimination. These differences could not be explained solely by variations in ascending thalamo-cortical input to SI. Instead, these results suggest that top-down influences during active discrimination may alter the overall functional nature of SI as well as layer-specific mechanisms of tactile processing.

@article{krupa2004, abstract = {Ensemble neuronal activity was recorded in each layer of the whisker area of primary somatosensory cortex (SI) while rats performed a whisker-dependent tactile discrimination. Comparison with SI activity evoked by similar passive whisker stimulation revealed fundamental differences in tactile signal processing during active and passive stimulation. Moreover, significant layer-specific functional differences in SI activity were observed during active discrimination. These differences could not be explained solely by variations in ascending thalamo-cortical input to SI. Instead, these results suggest that top-down influences during active discrimination may alter the overall functional nature of SI as well as layer-specific mechanisms of tactile processing.}, author = {Krupa, D. J. and Wiest, M. C. and Shuler, M. G. and Laubach, M. and Nicolelis, M. A. L. }, citeulike-article-id = {2437142}, journal = {Science}, keywords = {bibtex-import, sidartaproposal}, pages = {1989--1992}, posted-at = {2008-02-27 14:44:26}, priority = {2}, title = {Layer specific somatosensory cortical activation during active tactile discrimination}, volume = {304}, year = {2004} }

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TY - JOUR ID - krupa2004 L3 - citeulike-article-id:2437142 TI - Layer specific somatosensory cortical activation during active tactile discrimination JF - Science VL - 304 SP - 1989 EP - 1992 N2 - Ensemble neuronal activity was recorded in each layer of the whisker area of primary somatosensory cortex (SI) while rats performed a whisker-dependent tactile discrimination. Comparison with SI activity evoked by similar passive whisker stimulation revealed fundamental differences in tactile signal processing during active and passive stimulation. Moreover, significant layer-specific functional differences in SI activity were observed during active discrimination. These differences could not be explained solely by variations in ascending thalamo-cortical input to SI. Instead, these results suggest that top-down influences during active discrimination may alter the overall functional nature of SI as well as layer-specific mechanisms of tactile processing. KW - bibtex-import KW - sidartaproposal AU - Krupa, DJ AU - Wiest, MC AU - Shuler, MG AU - Laubach, M AU - Nicolelis, MAL PY - 2004/// ER -

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