Nitric oxide is a signal for NNR-mediated transcription activation in Paracoccus denitrificans.

@article{citeulike:2783975, abstract = {By using the 'lacZ gene, the activities of the nirI, nirS, and norC promoters were assayed in the wild type and in NNR-deficient mutants of Paracoccus denitrificans grown under various growth conditions. In addition, induction profiles of the three promoters in response to the presence of various nitrogenous oxides were determined. Transcription from the three promoters required the absence of oxygen and the presence both of the transcriptional activator NNR and of nitric oxide. The activity of the nnr promoter itself was halved after the cells had been switched from aerobic respiration to denitrification. This response was apparently not a result of autoregulation or of regulation by FnrP, since the nnr promoter was as active in the wild-type strain as it was in NNR- or FnrP-deficient mutants.}, address = {Department of Molecular Cell Physiology, Faculty of Biology, BioCentrum Amsterdam, Vrije Universiteit, NL-1081 HV Amsterdam, The Netherlands. spanning@bio.vu.nl}, author = {Van Spanning, R. J. and Houben, E. and Reijnders, W. N. and Spiro, S. and Westerhoff, H. V. and Saunders, N. }, citeulike-article-id = {2783975}, issn = {0021-9193}, journal = {Journal of bacteriology}, keywords = {nitric, nnr, oxide, paracoccus, regulation, transcription}, month = {July}, number = {13}, pages = {4129--4132}, posted-at = {2008-05-11 10:20:52}, priority = {2}, title = {Nitric oxide is a signal for NNR-mediated transcription activation in Paracoccus denitrificans.}, url = {http://view.ncbi.nlm.nih.gov/pubmed/10383987}, volume = {181}, year = {1999} }

TY - JOUR ID - citeulike:2783975 L3 - citeulike-article-id:2783975 TI - Nitric oxide is a signal for NNR-mediated transcription activation in Paracoccus denitrificans. JF - Journal of bacteriology VL - 181 IS - 13 SP - 4129 EP - 4132 AD - Department of Molecular Cell Physiology, Faculty of Biology, BioCentrum Amsterdam, Vrije Universiteit, NL-1081 HV Amsterdam, The Netherlands. spanning@bio.vu.nl SN - 0021-9193 N2 - By using the 'lacZ gene, the activities of the nirI, nirS, and norC promoters were assayed in the wild type and in NNR-deficient mutants of Paracoccus denitrificans grown under various growth conditions. In addition, induction profiles of the three promoters in response to the presence of various nitrogenous oxides were determined. Transcription from the three promoters required the absence of oxygen and the presence both of the transcriptional activator NNR and of nitric oxide. The activity of the nnr promoter itself was halved after the cells had been switched from aerobic respiration to denitrification. This response was apparently not a result of autoregulation or of regulation by FnrP, since the nnr promoter was as active in the wild-type strain as it was in NNR- or FnrP-deficient mutants. KW - nitric KW - nnr KW - oxide KW - paracoccus KW - regulation KW - transcription AU - Van Spanning, RJ AU - Houben, E AU - Reijnders, WN AU - Spiro, S AU - Westerhoff, HV AU - Saunders, N PY - 1999/07// UR - http://view.ncbi.nlm.nih.gov/pubmed/10383987 ER -