Both the Hippocampus and Striatum Are Involved in Consolidation of Motor Sequence Memory

@article{citeulike:2717522, abstract = {Summary Functional magnetic resonance imaging (fMRI) was used to investigate the cerebral correlates of motor sequence memory consolidation. Participants were scanned while training on an implicit oculomotor sequence learning task and during a single testing session taking place 30 min, 5 hr, or 24 hr later. During training, responses observed in hippocampus and striatum were linearly related to the gain in performance observed overnight, but not over the day. Responses in both structures were significantly larger at 24 hr than at 30 min or 5 hr. Additionally, the competitive interaction observed between these structures during training became cooperative overnight. These results stress the importance of both hippocampus and striatum in procedural memory consolidation. Responses in these areas during training seem to condition the overnight memory processing that is associated with a change in their functional interactions. These results show that both structures interact during motor sequence consolidation to optimize subsequent behavior.}, author = {Albouy, Genevi\`{e}ve and Sterpenich, Virginie and Balteau, Evelyne and Vandewalle, Gilles and Desseilles, Martin and Dang-Vu, Thanh and Darsaud, Annabelle and Ruby, Perrine and Luppi, Pierre-Herv\'{e} and Degueldre, Christian and Peigneux, Philippe and Luxen, Andr\'{e} and Maquet, Pierre }, citeulike-article-id = {2717522}, doi = {10.1016/j.neuron.2008.02.008}, journal = {Neuron}, keywords = {consolidation, fmri, hippocampus, striatum}, month = {April}, number = {2}, pages = {261--272}, posted-at = {2008-04-28 13:31:36}, priority = {2}, title = {Both the Hippocampus and Striatum Are Involved in Consolidation of Motor Sequence Memory}, url = {http://dx.doi.org/10.1016/j.neuron.2008.02.008}, volume = {58}, year = {2008} }

TY - JOUR ID - citeulike:2717522 TI - Both the Hippocampus and Striatum Are Involved in Consolidation of Motor Sequence Memory JF - Neuron VL - 58 IS - 2 SP - 261 EP - 272 N2 - Summary Functional magnetic resonance imaging (fMRI) was used to investigate the cerebral correlates of motor sequence memory consolidation. Participants were scanned while training on an implicit oculomotor sequence learning task and during a single testing session taking place 30 min, 5 hr, or 24 hr later. During training, responses observed in hippocampus and striatum were linearly related to the gain in performance observed overnight, but not over the day. Responses in both structures were significantly larger at 24 hr than at 30 min or 5 hr. Additionally, the competitive interaction observed between these structures during training became cooperative overnight. These results stress the importance of both hippocampus and striatum in procedural memory consolidation. Responses in these areas during training seem to condition the overnight memory processing that is associated with a change in their functional interactions. These results show that both structures interact during motor sequence consolidation to optimize subsequent behavior. KW - consolidation KW - fmri KW - hippocampus KW - striatum AU - Albouy, Geneviève AU - Sterpenich, Virginie AU - Balteau, Evelyne AU - Vandewalle, Gilles AU - Desseilles, Martin AU - Dang-Vu, Thanh AU - Darsaud, Annabelle AU - Ruby, Perrine AU - Luppi, Pierre-Hervé AU - Degueldre, Christian AU - Peigneux, Philippe AU - Luxen, André AU - Maquet, Pierre PY - 2008/04/24/ UR - http://dx.doi.org/10.1016/j.neuron.2008.02.008 ER -