Grasping the intentions of others: the perceived intentionality of an action influences activity in the superior temporal sulcus during social perception.

@article{citeulike:1224444, abstract = {An explication of the neural substrates for social perception is an important component in the emerging field of social cognitive neuroscience and is relevant to the field of cognitive neuroscience as a whole. Prior studies from our laboratory have demonstrated that passive viewing of biological motion (Pelphrey, Mitchell, et al., 2003; Puce et al., 1998) activates the posterior superior temporal sulcus (STS ) region. Furthermore, recent evidence has shown that the perceived context of observed gaze shifts (Pelphrey, Singerman, et al., 2003; Pelphrey et al., 2004) modulates STS activity. Here, using event-related functional magnetic resonance imaging at 4 T, we investigated brain activity in response to passive viewing of goal- and nongoal-directed reaching-to-grasp movements. Participants viewed an animated character making reaching-to-grasp movements either toward (correct) or away (incorrect) from a blinking dial. Both conditions evoked significant posterior STS activity that was strongly right lateralized. By examining the time course of the blood oxygenation level-dependent response from areas of activation, we observed a functional dissociation. Incorrect trials evoked significantly greater activity in the STS than did correct trials, while an area posterior and inferior to the STS (likely corresponding to the MT/ V5 complex) responded equally to correct and incorrect movements. Parietal cortical regions, including the superior parietal lobule and the anterior intraparietal sulcus, also responded equally to correct and incorrect movements, but showed evidence for differential responding based on the hand and arm (left or right) of the animated character used to make the reaching-to-grasp movement. The results of this study further suggest that a region of the right posterior STS is involved in analyzing the intentions of other people's actions and that activity in this region is sensitive to the context of observed biological motions.}, address = {Brain Imaging and Analysis Center, Duke University, Durham, NC 27710, USA.}, author = {Pelphrey, K. A. and Morris, J. P. and McCarthy, G. }, citeulike-article-id = {1224444}, doi = {10.1162/0898929042947900}, doi = {http://web.ebscohost.com/ehost/detail?vid=3\&hid=18\&sid=839f0e2e-f354-4cd6-867a-3e49610a6e88\%40sessionmgr9}, issn = {0898-929X}, journal = {J Cogn Neurosci}, keywords = {biological\_motion, cause\_and\_effect, intention, social\_perception, superior\_temporal\_sulcus}, month = {December}, number = {10}, pages = {1706--1716}, posted-at = {2007-04-13 18:44:00}, priority = {2}, title = {Grasping the intentions of others: the perceived intentionality of an action influences activity in the superior temporal sulcus during social perception.}, url = {http://dx.doi.org/10.1162/0898929042947900}, volume = {16}, year = {2004} }

TY - JOUR ID - citeulike:1224444 L3 - citeulike-article-id:1224444 TI - Grasping the intentions of others: the perceived intentionality of an action influences activity in the superior temporal sulcus during social perception. JF - J Cogn Neurosci VL - 16 IS - 10 SP - 1706 EP - 1716 AD - Brain Imaging and Analysis Center, Duke University, Durham, NC 27710, USA. SN - 0898-929X N2 - An explication of the neural substrates for social perception is an important component in the emerging field of social cognitive neuroscience and is relevant to the field of cognitive neuroscience as a whole. Prior studies from our laboratory have demonstrated that passive viewing of biological motion (Pelphrey, Mitchell, et al., 2003; Puce et al., 1998) activates the posterior superior temporal sulcus (STS ) region. Furthermore, recent evidence has shown that the perceived context of observed gaze shifts (Pelphrey, Singerman, et al., 2003; Pelphrey et al., 2004) modulates STS activity. Here, using event-related functional magnetic resonance imaging at 4 T, we investigated brain activity in response to passive viewing of goal- and nongoal-directed reaching-to-grasp movements. Participants viewed an animated character making reaching-to-grasp movements either toward (correct) or away (incorrect) from a blinking dial. Both conditions evoked significant posterior STS activity that was strongly right lateralized. By examining the time course of the blood oxygenation level-dependent response from areas of activation, we observed a functional dissociation. Incorrect trials evoked significantly greater activity in the STS than did correct trials, while an area posterior and inferior to the STS (likely corresponding to the MT/ V5 complex) responded equally to correct and incorrect movements. Parietal cortical regions, including the superior parietal lobule and the anterior intraparietal sulcus, also responded equally to correct and incorrect movements, but showed evidence for differential responding based on the hand and arm (left or right) of the animated character used to make the reaching-to-grasp movement. The results of this study further suggest that a region of the right posterior STS is involved in analyzing the intentions of other people's actions and that activity in this region is sensitive to the context of observed biological motions. KW - biological_motion KW - cause_and_effect KW - intention KW - social_perception KW - superior_temporal_sulcus AU - Pelphrey, KA AU - Morris, JP AU - McCarthy, G PY - 2004/12// UR - http://dx.doi.org/10.1162/0898929042947900 ER -