Sustained Activities and Retrieval in a Computational Model of the Perirhinal Cortex.

@article{citeulike:2707962, abstract = {Abstract The perirhinal cortex is involved not only in object recognition and novelty detection but also in multimodal integration, reward association, and visual working memory. We propose a computational model that focuses on the role of the perirhinal cortex in working memory, particularly with respect to sustained activities and memory retrieval. This model describes how different partial informations are integrated into assemblies of neurons that represent the identity of an object. Through dopaminergic modulation, the resulting clusters can retrieve the global information with recurrent interactions between neurons. Dopamine leads to sustained activities after stimulus disappearance that form the basis of the involvement of the perirhinal cortex in visual working memory processes. The information carried by a cluster can also be retrieved by a partial thalamic or prefrontal stimulation. Thus, we suggest that areas involved in planning and memory coordination encode a pointer to access the detailed information encoded in the associative cortex such as the perirhinal cortex.}, address = {Wilhelms-Universit\"{a}t M\"{u}nster, Germany.}, author = {Vitay, Julien and Hamker, Fred H H. }, citeulike-article-id = {2707962}, doi = {10.1162/jocn.2008.20147}, issn = {0898-929X}, journal = {Journal of cognitive neuroscience}, keywords = {heather, jie, kristina, memory-recall, perirhinal-cortex, shiva, working-memory}, month = {April}, posted-at = {2008-04-23 16:31:17}, priority = {2}, title = {Sustained Activities and Retrieval in a Computational Model of the Perirhinal Cortex.}, url = {http://dx.doi.org/10.1162/jocn.2008.20147}, year = {2008} }

TY - JOUR ID - citeulike:2707962 L3 - citeulike-article-id:2707962 TI - Sustained Activities and Retrieval in a Computational Model of the Perirhinal Cortex. JF - Journal of cognitive neuroscience AD - Wilhelms-Universität Münster, Germany. SN - 0898-929X N2 - Abstract The perirhinal cortex is involved not only in object recognition and novelty detection but also in multimodal integration, reward association, and visual working memory. We propose a computational model that focuses on the role of the perirhinal cortex in working memory, particularly with respect to sustained activities and memory retrieval. This model describes how different partial informations are integrated into assemblies of neurons that represent the identity of an object. Through dopaminergic modulation, the resulting clusters can retrieve the global information with recurrent interactions between neurons. Dopamine leads to sustained activities after stimulus disappearance that form the basis of the involvement of the perirhinal cortex in visual working memory processes. The information carried by a cluster can also be retrieved by a partial thalamic or prefrontal stimulation. Thus, we suggest that areas involved in planning and memory coordination encode a pointer to access the detailed information encoded in the associative cortex such as the perirhinal cortex. KW - heather KW - jie KW - kristina KW - memory-recall KW - perirhinal-cortex KW - shiva KW - working-memory AU - Vitay, Julien AU - Hamker, Fred H PY - 2008/04/16/ UR - http://dx.doi.org/10.1162/jocn.2008.20147 ER -